Here's how NATURE.COM makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

NATURE . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Nature.com Make Money
  6. How Much Does Nature.com Make
  7. Keywords
  8. Topics
  9. Questions
  10. Schema
  11. Social Networks
  12. External Links
  13. Analytics And Tracking
  14. Libraries
  15. Hosting Providers
  16. CDN Services

We are analyzing https://www.nature.com/articles/s41580-021-00342-0.

Title:
The expanding world of tRNA modifications and their disease relevance | Nature Reviews Molecular Cell Biology
Description:
Transfer RNA (tRNA) is an adapter molecule that links a specific codon in mRNA with its corresponding amino acid during protein synthesis. tRNAs are enzymatically modified post-transcriptionally. A wide variety of tRNA modifications are found in the tRNA anticodon, which are crucial for precise codon recognition and reading frame maintenance, thereby ensuring accurate and efficient protein synthesis. In addition, tRNA-body regions are also frequently modified and thus stabilized in the cell. Over the past two decades, 16 novel tRNA modifications were discovered in various organisms, and the chemical space of tRNA modification continues to expand. Recent studies have revealed that tRNA modifications can be dynamically altered in response to levels of cellular metabolites and environmental stresses. Importantly, we now understand that deficiencies in tRNA modification can have pathological consequences, which are termed ‘RNA modopathies’. Dysregulation of tRNA modification is involved in mitochondrial diseases, neurological disorders and cancer. Transfer RNAs (tRNAs) are heavily modified post-transcriptionally, and the number and types of modifications are continually expanding. Recent studies show that tRNA modifications can be altered in response to cellular and environmental stresses, and that deficiencies in tRNA modification can cause mitochondrial diseases, neurological disorders and cancer.
Website Age:
30 years and 10 months (reg. 1994-08-11).

Matching Content Categories {📚}

  • Education
  • Business & Finance
  • Science

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}


Display Ads {🎯}


The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.

Ads are managed by yourbow.com. Particular relationships are as follows:

Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.com

Reseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.com

How Much Does Nature.com Make? {💰}


Display Ads {🎯}

$63,100 per month
Our analysis indicates Nature.com generates between $42,042 and $115,616 monthly online from display ads.

Keywords {🔍}

pubmed, google, scholar, cas, central, trna, rna, biol, mitochondrial, modification, nat, modifications, cell, nature, trnas, res, genet, human, wobble, chem, suzuki, mol, nucleic, acids, cancer, transfer, anticodon, modified, protein, codon, rev, mutations, mutation, gene, hum, commun, translation, disease, embo, base, sci, article, position, role, acid, translational, taurine, molecular, diseases, access,

Topics {✒️}

scientific research nature portfolio journals permissions reprints deep-sequencing library preparation nature portfolio privacy policy advertising gsk-3beta-regulated n-acetyltransferase 10 social media translational research trna research exploratory research open-label liquid chromatography-mass spectrometry hplc-coupled mass spectrometry open growth phase-dependent alteration author information authors thermus thermophilus ef-tu mitochondria-localized heteromeric transglycosylase nature+ nature 336 nature 554 nature 348 nature 534 nature 558 nature 253 nature trna-derived small rnas isoleucyl-transfer rna synthetase phenylalanine-specific transfer rnas editing mtu1-mediated thiouridine formation co2-sensitive trna modification human trna-guanine transglycosylase enzymatically modified post-transcriptionally ragged-red fiber disease universal kae1/qri7/ygjd personal data peer review mt-trnamet wobble cytosine early-onset mitochondrial encephalomyopathy s-adenosylmethionine-binding protein diet-induced evolutionary adaptations multiple respiratory-chain deficiencies de crecy-lagard de crecy-lagard single post-transcriptional modification mitochondrial-trna modifier mto1 autosomal-recessive intellectual disability

Questions {❓}

  • Is taurine a functional nutrient?
  • Myoclonus epilepsy associated with ragged-red fibres (mitochondrial abnormalities): disease entity or a syndrome?
  • RNA modifications: what have we learned and where are we headed?
  • Transfer RNA bound to MnmH protein is enriched with geranylated tRNA–a possible intermediate in its selenation?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:The expanding world of tRNA modifications and their disease relevance
         description:Transfer RNA (tRNA) is an adapter molecule that links a specific codon in mRNA with its corresponding amino acid during protein synthesis. tRNAs are enzymatically modified post-transcriptionally. A wide variety of tRNA modifications are found in the tRNA anticodon, which are crucial for precise codon recognition and reading frame maintenance, thereby ensuring accurate and efficient protein synthesis. In addition, tRNA-body regions are also frequently modified and thus stabilized in the cell. Over the past two decades, 16 novel tRNA modifications were discovered in various organisms, and the chemical space of tRNA modification continues to expand. Recent studies have revealed that tRNA modifications can be dynamically altered in response to levels of cellular metabolites and environmental stresses. Importantly, we now understand that deficiencies in tRNA modification can have pathological consequences, which are termed ‘RNA modopathies’. Dysregulation of tRNA modification is involved in mitochondrial diseases, neurological disorders and cancer. Transfer RNAs (tRNAs) are heavily modified post-transcriptionally, and the number and types of modifications are continually expanding. Recent studies show that tRNA modifications can be altered in response to cellular and environmental stresses, and that deficiencies in tRNA modification can cause mitochondrial diseases, neurological disorders and cancer.
         datePublished:2021-03-03T00:00:00Z
         dateModified:2021-03-03T00:00:00Z
         pageStart:375
         pageEnd:392
         sameAs:https://doi.org/10.1038/s41580-021-00342-0
         keywords:
            RNA modification
            tRNAs
            Life Sciences
            general
            Cell Biology
            Cancer Research
            Developmental Biology
            Stem Cells
            Biochemistry
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-021-00342-0/MediaObjects/41580_2021_342_Fig1_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-021-00342-0/MediaObjects/41580_2021_342_Fig2_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-021-00342-0/MediaObjects/41580_2021_342_Fig3_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-021-00342-0/MediaObjects/41580_2021_342_Fig4_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-021-00342-0/MediaObjects/41580_2021_342_Fig5_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-021-00342-0/MediaObjects/41580_2021_342_Fig6_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-021-00342-0/MediaObjects/41580_2021_342_Fig7_HTML.png
         isPartOf:
            name:Nature Reviews Molecular Cell Biology
            issn:
               1471-0080
               1471-0072
            volumeNumber:22
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Tsutomu Suzuki
               url:http://orcid.org/0000-0002-9731-1731
               affiliation:
                     name:The University of Tokyo
                     address:
                        name:Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:The expanding world of tRNA modifications and their disease relevance
      description:Transfer RNA (tRNA) is an adapter molecule that links a specific codon in mRNA with its corresponding amino acid during protein synthesis. tRNAs are enzymatically modified post-transcriptionally. A wide variety of tRNA modifications are found in the tRNA anticodon, which are crucial for precise codon recognition and reading frame maintenance, thereby ensuring accurate and efficient protein synthesis. In addition, tRNA-body regions are also frequently modified and thus stabilized in the cell. Over the past two decades, 16 novel tRNA modifications were discovered in various organisms, and the chemical space of tRNA modification continues to expand. Recent studies have revealed that tRNA modifications can be dynamically altered in response to levels of cellular metabolites and environmental stresses. Importantly, we now understand that deficiencies in tRNA modification can have pathological consequences, which are termed ‘RNA modopathies’. Dysregulation of tRNA modification is involved in mitochondrial diseases, neurological disorders and cancer. Transfer RNAs (tRNAs) are heavily modified post-transcriptionally, and the number and types of modifications are continually expanding. Recent studies show that tRNA modifications can be altered in response to cellular and environmental stresses, and that deficiencies in tRNA modification can cause mitochondrial diseases, neurological disorders and cancer.
      datePublished:2021-03-03T00:00:00Z
      dateModified:2021-03-03T00:00:00Z
      pageStart:375
      pageEnd:392
      sameAs:https://doi.org/10.1038/s41580-021-00342-0
      keywords:
         RNA modification
         tRNAs
         Life Sciences
         general
         Cell Biology
         Cancer Research
         Developmental Biology
         Stem Cells
         Biochemistry
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-021-00342-0/MediaObjects/41580_2021_342_Fig1_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-021-00342-0/MediaObjects/41580_2021_342_Fig2_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-021-00342-0/MediaObjects/41580_2021_342_Fig3_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-021-00342-0/MediaObjects/41580_2021_342_Fig4_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-021-00342-0/MediaObjects/41580_2021_342_Fig5_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-021-00342-0/MediaObjects/41580_2021_342_Fig6_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-021-00342-0/MediaObjects/41580_2021_342_Fig7_HTML.png
      isPartOf:
         name:Nature Reviews Molecular Cell Biology
         issn:
            1471-0080
            1471-0072
         volumeNumber:22
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Tsutomu Suzuki
            url:http://orcid.org/0000-0002-9731-1731
            affiliation:
                  name:The University of Tokyo
                  address:
                     name:Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature Reviews Molecular Cell Biology
      issn:
         1471-0080
         1471-0072
      volumeNumber:22
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:The University of Tokyo
      address:
         name:Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Tsutomu Suzuki
      url:http://orcid.org/0000-0002-9731-1731
      affiliation:
            name:The University of Tokyo
            address:
               name:Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(2)

External Links {🔗}(617)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Prism.js
  • Zoom.js

Emails and Hosting {✉️}

Mail Servers:

  • mxa-002c5801.gslb.pphosted.com
  • mxb-002c5801.gslb.pphosted.com

Name Servers:

  • pdns1.ultradns.net
  • pdns2.ultradns.net
  • pdns3.ultradns.org
  • pdns4.ultradns.org
  • pdns5.ultradns.info
  • pdns6.ultradns.co.uk

CDN Services {📦}

  • Crossref

4.72s.