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Title[redir]:
The hyperthermophilic partners Nanoarchaeum and Ignicoccus stabilize their tRNA T-loops via different but structurally equivalent modifications - PMC
Description:
The universal L-shaped tertiary structure of tRNAs is maintained with the help of nucleotide modifications within the D- and T-loops, and these modifications are most extensive within hyperthermophilic species. The obligate-commensal Nanoarchaeum ...
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Keywords {๐}
equitans, google, scholar, doi, pubmed, trna, hospitalis, trnas, figure, pmc, neq, article, modification, free, rna, nucleotide, compound, rrna, modifications, supplementary, msu, mass, structure, enzyme, coli, fragmentation, methyltransferase, enzymes, nucleosides, archaea, acids, uridine, nucleic, grosjean, msฯ, archaeal, group, nucleotides, modified, res, nucleoside, ion, position, pab, comparison, data, recombinant, previously, methyl, methylation,
Topics {โ๏ธ}
folate/fad-dependent trna methyltransferase fad/folate-dependent trna methyltransferase core l-shaped conformation s-adenosyl-l-methionine s-adenosylmethionine-dependent enzyme neq053 phylogenetically-unrelated mechanism directed distinct structurally-equivalent solutions valรฉrie de crรฉcy-lagard pmc beta search trma null-strain lacking trma null-strain recombinants double-stranded dna template folate-dependent enzymes trmfo negative/positive ion modes d-loops lack dihydrouridine bacterial ruma-type trna ion-trap esi-ms obligate-commensal nanoarchaeum equitans license information pmcid unique nanoarchaeum/ignicoccus association collision-induced fragmentation generated iron-sulfur protein ttua mass accuracy/isotope considerations base-fragmentation pattern identical [google scholar] 2 [google scholar] 3 [google scholar] 4 [google scholar] 17 16s rrna-specific recombinant transfer rna m5u54-methyltransferase maldi-tof mass spectrometry ms/ms fragmentation pattern u54-specific counterpart trma lc/esi-ms analyses folate-dependent methylation involving s-adenosylmethionine folate-dependent trna esi-ms analyses confirmed oligonucleotide-rrna hybrids negative ion modes igni_0707 resembles neq283 pyrimidine c5-methylation targets structurally equivalent manner nucleic acids research eleven distinct derivatives negative ion mode additional data file possess structural solutions ribosomal ribonucleic acid ribosomal binding sites
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