
NCBI . NLM . NIH . GOV {
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Title[redir]:
Structural insights into the translational infidelity mechanism - PMC
Description:
The decoding of mRNA on the ribosome is the least accurate process during genetic information transfer. Here we propose a unified decoding mechanism based on 11 high-resolution X-ray structures of the 70S ribosome that explains the occurrence of ...
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Keywords {đ}
trna, ribosome, doi, pubmed, google, scholar, decoding, codonanticodon, fig, mrna, pmc, article, supplementary, mismatch, centre, free, pair, watsoncrick, mismatches, psite, anticodon, ribosomal, geometry, ribosomes, position, structures, nearcognate, pairs, structure, complexes, asite, data, duplex, positions, cognate, interactions, errors, codon, rrna, biol, mechanism, translation, binding, selection, protein, rna, formation, buffer, translational, infidelity,
Topics {âď¸}
single-photon-counting pixel detectors p-site codonâanticodon mini-helix optimal fine phi-slicing pmc beta search visualizing transient watson-crick codonâanticodon mini-helices codonâanticodon mini-helix11 low-populated watsonâcrick comprehensive python-based system x-ray crystal structures isotropic b-factor refinement mistranslation-induced protein misfolding maintain watsonâcrick geometry watsonâcrick pair matching canonical watsonâcrick pairs codonâanticodon duplex entrapped codonâanticodon duplex play codonâanticodon mini-helix ďż˝challenging' pyrimidineâpurine mismatch mini-helical structure due standard watsonâcrick pairs canonical watsonâcrick pair steady-state enzymatic system discussed base-pairing schemes p-site transfer rna12 post-incorporation state based watson-crick base pairs 70s/trnafmet/mrna-6 mixtures 70s/trnafmet/mrna-8 mixtures trna anticodon stem-loop12 references drummond a-minor groove interactions genetic information transfer flow rate 6âmlâminâ1 average 400-codon-long gene ketoâenol tautomeric equilibrium establishing codonâanticodon interactions full 70s ribosome exit trna-binding sites mismatch forms watsonâcrick 70s/trnafmet/mrna-5 mixture license information pmcid x-ray crystallography codonâanticodon position provided anr-10-labx-0036_netrna peptidyl-trna-binding site additional intersubunit bridge methods ribosome purification 70s/trnafmet/mrna-6/trnaphe aminoacyl-trna-binding site
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- What's the income generated by https://scholar.google.com/scholar_lookup?journal=Acta%20Crystallogr.%20D%20Biol.%20Crystallogr.&title=PHENIX:%20a%20comprehensive%20Python-based%20system%20for%20macromolecular%20structure%20solution&author=P.%20D.%20Adams&volume=66&publication_year=2010&pages=213-221&pmid=20124702&doi=10.1107/S0907444909052925& each month?
- What's the income generated by https://doi.org/10.1107/S0907444910007493 each month?
- https://scholar.google.com/scholar_lookup?journal=Acta%20Crystallogr.%20D%20Biol.%20Crystallogr.&title=Features%20and%20development%20of%20Coot&author=P.%20Emsley&author=B.%20Lohkamp&author=W.%20G.%20Scott&author=K.%20Cowtan&volume=66&publication_year=2010&pages=486-501&pmid=20383002&doi=10.1107/S0907444910007493&'s revenue stream
- https://doi.org/10.1038/nsmb.2003's financial summary
- How much income does https://scholar.google.com/scholar_lookup?journal=Nat.%20Struct.%20Mol.%20Biol.&title=How%20mutations%20in%20tRNA%20distant%20from%20the%20anticodon%20affect%20the%20fidelity%20of%20decoding&author=T.%20M.%20Schmeing&author=R.%20M.%20Voorhees&author=A.%20C.%20Kelley&author=V.%20Ramakrishnan&volume=18&publication_year=2011&pages=432-436&pmid=21378964&doi=10.1038/nsmb.2003& have?
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- Check the income stats for https://github.com/ncbi
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- How much does https://www.nlm.nih.gov/web_policies.html bring in each month?
- Profit of https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office
- Revenue of https://www.hhs.gov/vulnerability-disclosure-policy/index.html
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Analytics and Tracking {đ}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {đ}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {âď¸}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {đŚ}
- Ncbi