
NCBI . NLM . NIH . GOV {
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Title[redir]:
The expression of TRMT2A, a novel cell cycle regulated protein, identifies a subset of breast cancer patients with HER2 over-expression that are at an increased risk of recurrence - PMC
Description:
Over-expression of HER2 in a subset of breast cancers (HER2+) is associated with high histological grade and aggressive clinical course. Despite these distinctive features, the differences in response of HER2+ patients to both adjuvant cytotoxic ...
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Keywords {π}
trmta, patients, doi, cancer, breast, clinical, staining, outcome, expression, cohort, antibody, ccih, independent, cohorts, pubmed, google, scholar, ccf, tumor, adjuvant, association, rpci, email, chemotherapy, trastuzumab, study, monoclonal, cell, recurrence, therapy, treatment, positive, receptor, data, cases, pmc, protein, antibodies, directed, prognostic, tissue, stage, polyclonal, grade, univariate, analysis, gene, clin, nlm, risk,
Topics {βοΈ}
pre-publication history double-stranded dna-binding factors 20307320 abstract background polyclonal affinity-purified antibodies pmc beta search tab discussion her2-positive breast cancer aid clinical decision-making references arnedos her2+/trmt2a+ breast cancers publisher site pdf archived tumor samples license information pmcid disease free survival cox proportional hazards human breast cancer tissue array sections recurrence-free interval breast cancer cases breast cancer specimens assay methods metastatic breast cancer conclusion results discovery study human breast tumours authors approved clinical follow gene expression patterns shown inconsistent results[14] clin breast cancer er+ breast cancer clearview cancer institute tab tissue arrays 2-year follow regulate dna replication breast cancer patients rabbit monoclonal antibody breast tumor classification[16] breast tumor subtypes emerging targeted therapies ccih tissue array[16] large project aimed original polyclonal antibody similar expression patterns representative paraffin blocks human cell cycle mol biol cell herceptestβ’ test kit identical 38kd bands ncbi databases
Questions {β}
- Molecular classification and molecular forecasting of breast cancer: ready for clinical application?
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