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Title[redir]:
Essentiality of threonylcarbamoyladenosine (t6A), a universal tRNA modification, in bacteria - PMC
Description:
Threonylcarbamoyladenosine (t6A) is a modified nucleoside universally conserved in tRNAs in all three kingdoms of life. The recently discovered genes for t6A synthesis, including tsaC and tsaD, are essential in model prokaryotes but not essential in ...
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Keywords {🔍}
doi, google, scholar, pubmed, coli, trna, pmc, article, free, protein, genes, essential, radiodurans, tils, gene, table, ilers, growth, essentiality, synthesis, analysis, strains, figure, bacteria, modification, absence, mutant, trnas, yeast, enzymes, proteins, strain, vdc, tsac, mutans, codons, codon, wildtype, levels, data, mol, results, biol, tsad, translation, acids, minutes, determinant, thermophilus, cell,
Topics {✒️}
udp-n-acetyl-d-mannosaminuronic acid transferase primer pairs ptet2771-fwd/ygjd661-rev supp info nihms801381-supplement-supp_info glucosamine--fructose-6-phosphate aminotransferase [isomerizing] peptidyl-prolyl cis-trans isomerase n-acetylmuramoyl-l-alanine amidase d-alanine--d-alanine ligase short-chain dehydrogenase/reductase family cold-shock dead-box protein yeast-soluble cell-free extracts eukaryotic-type isoleucyl-trna synthetases ptet2771-fwd/yrdc573-rev [google scholar] gieg� peptidyl transferase reaction [google scholar] msadek trnaile lysidine synthetase acceptor stem stadler pf b12-binding component btuf [google scholar] nureki [google scholar] sarmiento single-cell time-lapse analysis cancer-testis antigen defines vdc7073 c600 ptet∷tsac∷aph vdc5801 bw25113 ptet∷tsad∷aph pmc beta search vdc7069 c600 ptet∷tsad∷aph eubacterial-specific antisynthetase drug isoleucyl trna synthetase isoleucyl-trna synthetase trm9-catalyzed trna modifications nanolc-esi ms/ms vdc5684 bw25113 ptet∷tsac∷aph transposon-mediated differential hybridisation base pairs c4-g69 periplasmic substrate-binding protein large-scale transposon mutagenesis thij/pfpi family protein ms/ms spectra assigned liquid chromatography-mass spectrometry plant-prokaryote comparative genomics intermediate threonylcarbamoyl-amp targeted ms/ms approach irradiation-induced dna damage ψ-modified base/m22g agris anhydrotetracycline thermostable kanamycin-resistant marker experimental procedures bioinformatics predicted l-lactate dehydrogenase
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- Archaeal aminoacyl-tRNA synthesis: unique determinants of a universal genetic code?
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