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Keywords {🔍}

mice, mitochondrial, mtu, mtulko, fig, liver, translation, levels, hepatocytes, lko, doi, google, scholar, pubmed, rilf, flox, pmc, modification, article, mtudeficient, mtuflox, livers, modifications, data, free, patients, knockout, exhibited, deficiency, stress, tif, weekold, relative, control, mutations, oxidative, results, representative, respiratory, mttrnas, shown, injury, molecular, dysfunction, mouse, protein, examined, trnas, gene, genes,

Topics {✒️}

generated liver-specific mtu1-deficient muscle-specific mtu1-deificient mice hepatocyte-specific mtu1 knockout generated liver-specific knockout liver-bone endocrine relay von kleist-retzow jc mt-trna-modifying enzymes pmc beta search primerscript rt-pcr kit glucose-6-phosphatase catalytic subunit cdk5rap1-mediated 2-methylthio modification high-density lipoprotein cholesterol mitochondrial mt-tf variant low-density lipoprotein cholesterol trna-modifying enzymes mitochondrial aspartyl-trna synthetase life-threatening condition characterized blood vessel networks mtu1-mediated 2-thiouridine formation [google scholar] 5 adult mtu1-deficient mice mtu1-mediated mitochondrial translation induced liver injury mtu1-deficient primary hepatocytes selected metabolism-related genes infantile reversible cytochrome mtu1-deficient hepatocytes compared mtu1-mediated s2 modification mtdna-encoded mitochondrial genes oxidative stress-related metabolites aberrant structures magnified liver injury characterized constitutive knockout mice respiratory chain deficiency mt-trnalys remained unchanged blue-native page developmental stage-matched tissues fully modified mt-trnas data availability statement exhibited normal translation catastrophic liver failure dars2 knockout mice liver injury occurs publisher site pdf severe mitochondrial dysfunction strain-specific differences mt-trnalys contained τm5s2u bacterial trnagln lacking 12% sds-page gels mtu1-deficient liver

Questions {❓}

• Why is Mtu1-mediated s2 modification crucial for mitochondrial translation?

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• jQuery
• jQuery module (jquery-3.6.0)
• Zoom.js

Emails and Hosting {✉️}

Mail Servers:

• nihcesxway.hub.nih.gov
• nihcesxway2.hub.nih.gov
• nihcesxway3.hub.nih.gov
• nihcesxway4.hub.nih.gov
• nihcesxway5.hub.nih.gov

Name Servers:

• dns1-ncbi.ncbi.nlm.nih.gov
• dns2-ncbi.ncbi.nlm.nih.gov
• lhcns1.nlm.nih.gov
• lhcns2.nlm.nih.gov

CDN Services {📦}

• Ncbi