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Title[redir]:
The yeast rapid tRNA decay pathway competes with elongation factor 1A for substrate tRNAs and acts on tRNAs lacking one or more of several modifications - PMC
Description:
The structural and functional integrity of tRNA is crucial for translation. In the yeast Saccharomyces cerevisiae, certain aberrant pre-tRNA species are subject to nuclear surveillance, leading to 3′ exonucleolytic degradation, and certain mature ...
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Keywords {🔍}
trmδ, rtd, mutants, trna, strains, doi, pubmed, google, scholar, temperature, rna, pmc, trnas, article, efa, species, tanδ, free, trnasercga, trnaseruga, levels, tefδ, sensitivity, yeast, pathway, degradation, subject, trnavalaac, reduced, media, modifications, tef, fig, grown, mutation, due, lack, figure, mutant, chernyakov, translation, results, alexandrov, charged, open, thiolutin, whipple, overexpression, strain, shift,
Topics {✒️}
trm8-δ pus7-δ tef1-δ trm8-δ trm4-δ mutant trm8-δ dus3-δ mutant trm8-δ trm4-δ [tef1] trm8-δ pus7-δ mutant trm8-δ trm4-δ strain trm8-δ trm4-δ mutants elp3-δ tuc1-δ mutants trm1-δ trm4-δ mutants trm8-δ dus3-δ mutants tan1-δ trm44-δ mutant trm8-δ pus7-δ mutants tan1-δ trm44-δ [tef1] trm8-δ trm4-δ strains tan1-δ trm44-δ mutants trm1-δ trm4-δ strains trm8-δ tef1-δ mutants trm1-δ tef1-δ strain trm1-δ tef1-δ mutants tan1-δ trm44-δ strains trm8-δ trm4-δ [tef2] trm1-δ single-mutant strain trm1-δ tef1-δ strains tan1-δ tef1-δ strains trm1-δ single-mutant strains trm8-δ trm4-δ trm8-δ dus3-δ trm8-δ pus7-δ tan1-δ trm44-δ trm8-δ tef1-δ trm1-δ tef1-δ tef1-δ mutation enhances common trm8-δ mutation trm1-δ single mutants tef1-δ mutation exacerbates tef1-δ–derivative strains tef1-δ mutation leads pmc beta search rapid large-scale purification murphy fv 4th trm8-δ mutant single post-transcriptional modification tan1-δ mutant trm8-δ mutants trm1-δ strain trm1-δ mutants [2μ leu2 trnaser tef1-δ mutants tan1-δ mutants characterized high-copy suppressors
Questions {❓}
- Do all modifications benefit all tRNAs?
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