
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Stem cell function and stress response are controlled by protein synthesis - PMC
Description:
Whether protein synthesis and cellular stress response pathways interact to control stem cell function is currently unknown. Here, we show that skin stem cells synthesize less protein than their immediate progenitors in vivo, even when forced to ...
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Keywords {🔍}
cells, nsun, doi, data, cell, tumours, protein, fig, rna, google, scholar, pubmed, synthesis, translation, mice, extended, stem, skin, pmc, article, mouse, free, human, tumour, ribosome, hair, ksosnsun, trna, expression, methylation, analysis, reads, samples, oppuro, performed, figure, epidermal, fragments, stress, ksos, supplementary, open, anagen, fibroblasts, nature, control, sequencing, illumina, translational, transcripts,
Topics {✒️}
org/packages/release/bioc/html/deseq2 org/packages/release/bioc/html/deseq rosa-cag-lsl-tdtomato mice dmba-tpa-induced malignant progression supplementary tables nihms68287-supplement-supplementary_tables org/info/data/ftp/index inhibiting angiogenin-mediated trna-cleavage1 cap-independent stress-response programme4 high-level beta1-integrin expression patient-derived nsun2-deficient fibroblasts k5-sos-fxwa2/wa2 mice org/info/data/ftp adapter-trimmed trna-seq reads autosomal-recessive intellectual disability adapter-trimmed ribo-seq reads k5-sos/nsun2-/- mice developed k5-sos-fxwa2/+xnsun2-/ k5-sos-fxwa2/+xnsun2+/ nsun2-expressing itgα6-/ivl+ cells k5-sos/nsun2-/- cutaneous tumors �nonsense-mediated decay’ types denr-mct-1 promotes translation pmc beta search transgenic k5-sos/nsun2+/+ k5-sos/nsun2-/- skin tumours medical research council pe-cy7-conjugated cd117 tumour-initiating cells synthesize newborn apc-egfp mice k5-sos/nsun2-/- tumour samples chicken polyclonal anti-gfp k5-sos transgenic mice de/htseq/doc/overview genome-wide translational profiling k190m-expressing itgα6+/ivl- cells integrin/focal adhesion kinase generate mrna-seq libraries gender-matching individual compared wellcome trust mediates myc-induced proliferation nsun2-dependent methylation occurred k5-sos-fxwa2/+nsun2+/+ nsun2-mediated cytosine-5 methylation mesenchymal transition-related gene k5-sos/nsun2-/- littermates tumor-initiating stem cells showing op-puro incorporation real-time pcr amplification k5-sos tumours expressing k5-sos-fxwa2/+ mice
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