DOI . ORG {}

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We began analyzing https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-018-0766-4, but it redirected us to https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-018-0766-4. The analysis below is for the second page.

Title[redir]:
New insights into the regulatory role of microRNA in tumor angiogenesis and clinical implications | Molecular Cancer | Full Text
Description:
Angiogenesis is essential for tumor growth and metastasis. Understanding the regulation of tumor angiogenesis has become increasingly important. MicroRNAs (miRNAs) are small noncoding RNAs that function in diverse biological processes via post-transcriptional regulation. Extensive studies have revealed two important regulatory roles of miRNAs in tumor angiogenesis: miRNAs in tumor cells affect the activity of endothelial cells via non-cell-autonomous mechanisms, and miRNAs in endothelial cells regulate the cell-autonomous behavior. Recent advances have further highlighted the role of tumor-derived extracellular vesicles in the regulation of tumor angiogenesis via transferring miRNAs to endothelial cells. In this review, we summarize the regulatory role of miRNA in tumor angiogenesis, with a highlight on clinical implications of miRNAs as biomarkers for anti-angiogenic therapy response, and as therapeutic interventions against tumor angiogenesis in vivo.

Matching Content Categories {📚}

Education
Science
Health & Fitness

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Custom-built

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🚀 Good Traffic: 50k - 100k visitors per month

Based on our best estimate, this website will receive around 50,019 visitors per month in the current month.
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Keywords {🔍}

pubmed, angiogenesis, article, google, scholar, tumor, cas, cancer, mirnas, cells, central, cell, targeting, growth, endothelial, mirna, microrna, antiangiogenic, ecs, delivery, regulation, expression, response, angiogenic, exosomes, therapy, therapeutic, vegf, target, factor, biomarkers, treatment, vascular, signaling, inhibits, biol, vivo, role, metastasis, vegfa, patients, table, carcinoma, mira, nat, evs, predictive, lung, including, regulatory,

Topics {✒️}

cyclic arginine-glycine-aspartic acid aprpg-peg-modified lipoplexes accumulated mirna-181b suppresses igf-1r pik3c2alpha/akt/hif-1alpha pathway endothelial-specific intron-derived mir-126 nucleic acid-based drugs cell-derived membrane vesicles multi-targeted anti-angiogenic approach tumor-derived extracellular vesicles hepatoma-derived growth factor 2-dioleoyl- sn-glycero-3-phosphatidylcholine references hanahan myc/mycn-activated microrna springer nature myc-activated microrna cluster mir-125b induced formation node-negative breast carcinoma injected mir-125b directly induce pro-angiogenic effects regulating microrna-29b expression cancer cell-derived mirna human esc-derived mscs cell-derived microvesicles mediate finally enhanced hif-1α anti-angiogenic signals elicited microrna-425-3p predicts response lower mir-455-5p level pro-angiogenic gene adrenomedullin microrna-26a inhibits angiogenesis ev-encapsulated mir-9 transferred rna-induced silencing complex dependent exosomal transfer anti-angiogenic therapy response stable blood-based markers mv-delivered antisense rna tumor cell-derived evs jak-stat pathway activation privacy choices/manage cookies authors scientific editing cancer cell-derived evs higher mir-664-3p level real-time pcr data exosomal mir-105 derived mirna delivery system stably transfer mir-29a/ predominant growth factor placental growth factor poor progression-free survival article wang bmc

Questions {❓}

Effects of anti-miR-182 on TSP-1 expression in human colon cancer cells: there is a sense in antisense?
In vivo gene delivery by nonviral vectors: overcoming hurdles?

Schema {🗺️}

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