
NCBI . NLM . NIH . GOV {
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Title[redir]:
miRNA-27b Targets Vascular Endothelial Growth Factor C to Inhibit Tumor Progression and Angiogenesis in Colorectal Cancer - PMC
Description:
Colorectal cancer (CRC) is one of the most prevalent cancers globally and is one of the leading causes of cancer-related deaths due to therapy resistance and metastasis. Understanding the mechanism underlying colorectal carcinogenesis is essential ...
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Keywords {🔍}
mirb, cells, crc, cancer, tumor, expression, pubmed, doi, cell, google, scholar, vegfc, figure, growth, assay, data, angiogenesis, results, tissues, cscs, mirna, pmc, role, target, tumors, antimirb, vivo, colorectal, xenograft, article, mirnas, stem, mice, file, metastasis, proliferation, usa, levels, luciferase, bars, factor, colony, mimics, free, progression, targeting, hypermethylation, therapeutic, qpcr, group,
Topics {✒️}
5-dimethylthiazol-2-yl]-5-[3-carboxymethoxyphenyl]-2-[4-sulfophenyl]-2h-tetrazolium salt anti-mir-27b promoted growth primary antibodies anti-human-vegfc anti-mir-27b stable cells platelet-derived growth factor 1 od mimics/time/mouse mitogen-activated protein kinase anti-mir-27b mimics mirna-mediated promoter hypermethylation prl-tk-luciferase plasmids mir-130b promotes cd133 cancer-related deaths due soft-agar colony assay anti-mir-27b mimic mir-27b cpg island methyltransferase inhibitor 5-aza-dc bearing nod/scid mice mir-27b targets ppargamma mir-27b expression differed mir-27b target site hsa-mir-200b cluster cholesterol-conjugated negative control potent anti-tumor effects pmc beta search female nod/scid mice mir-27b expression decreased decreased mir-27b expression prl-tk renilla luciferase predicted mir-27b targets cholesterol-conjugated mimics paired paraffin-embedded tissues supplementary materials included mirna-based therapeutic strategies therapeutic anti-tumor agent mir-27b expression assessed mir-27b xenografts compared measured mir-27b expression emerging evidence supporting cell signaling pathways rnase-free dnase 1 nmol/ml tsa advanced breast cancer prl-tk plasmids predicted promoter site tip cell fate anti-mir-27b inhibiting mir-27b cpg island hypermethylation anti-human gapdh cholesterol-conjugated nc
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