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Title[redir]:
MiR-590-5p inhibits colorectal cancer angiogenesis and metastasis by regulating nuclear factor 90/vascular endothelial growth factor A axis - PMC
Description:
Altered expression of microRNA-590-5p (miR-590-5p) is involved in tumorigenesis, however, its role in colorectal cancer (CRC) remains to be determined. In this study, we focused on examining the effects of different expression levels of miR-590-5p ...
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Keywords {🔍}
mirp, crc, cells, expression, cancer, figure, tumor, pubmed, google, scholar, cell, doi, vegfa, angiogenesis, pmc, control, levels, article, protein, free, metastasis, primir, compared, tissues, growth, normal, colorectal, mice, results, human, knockdown, mirna, significantly, assay, factor, negative, data, found, transfected, min, role, vegf, target, mirnas, analysis, inhibitor, mature, gene, supplementary, performed,
Topics {✒️}
epithelial–mesenchymal transition severe combined immunodeficient 3′-untranslated region conditioned media rna-induced silencing complex au-binding protein precursor mirna epithelial micrornas phu6-puro-nf90-shrna lentivirus particles nuclear factor 90 putative mir-590-5p-binding site dna-binding complex regulating mir-590-5p knockdown-induced angiogenesis rna-binding proteins primary mirna epithelial ovarian combined action mir-590-5p-dependent post-transcriptional repression emsa emsa putative predictive factor interleukin-2 mrna stabilization emt-related proteins membrane silencing vegfa small-interfering rna ilf3 pre-mirna 100 nm psicheck-2-nf90 3′utr sheep anti-dig-horseradish peroxidase normal hiecs 25 mirna-chip assays inhibited mirna processing mir-590-5p-deleted cells grown enzyme-linked immunosorbent assay mature mirna duplexes mirna-dependent pathway angiogenesis induced nf90-nf45 complex functions sheep anti-dig-hrp conjugate mirna processing pathway mirna regulatory network crc induced interleukin-2 psicheck-2-mut-nf90 3′utr primary tumor sites scid mice pri-mirna primary crc samples radio-immunoprecipitation assay buffer hiecs
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