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Keywords {🔍}

doi, expression, cells, hifα, cancer, vegf, cell, hypoxia, hct, colon, pubmed, google, scholar, human, pmc, transfected, premir, article, fig, free, media, control, microrna, regulates, tumor, overexpression, inhibits, data, factor, endothelial, signaling, mirna, hif, angiogenesis, target, protein, normal, utr, levels, specimens, mrna, normoxia, mirnas, growth, lines, figure, exposed, huvec, luciferase, plos,

Topics {✒️}

org/cgi-bin/mirnaviewer/mirnaviewer 32p-end-labeled probes specific proto-oncogenic pten-targeting intron pmir-report luciferase vector c-myc binding protein rna-induced silencing complex quantitative real-time pcr pmc beta search tumor-suppressive microrna-22 inhibits mir-107 inhibits hif-1β[34] hypoxia induces hif-1α mir-22 suppresses hif-1α mir-22 regulates ppar-alpha hypoxia-inducible factor-1alpha suppressing hif-1α expression mir-22 regulates hif-1α mir-106b∼25 microrna cluster affect hif-1α mrna performed real-time pcr human hif-1α 3′utr c-myc target genes control hif-1α translation c-myc decreases potential binding site license information pmcid supplementary materials included mir-22 binding site inhibiting hif-1α expression publisher site pdf modulates tumor growth suppressing tumor growth represses estrogen signaling endothelial cell growth mouse hif-1α human colon cancer targeting hif-1 alpha repress protein translation[3] involves endothelial migration tmb peroxidase substrate normal colon specimens hypoxia-inducible factor 1 regulate hif-1 protein anti-sense-mir-22 cancer cell lines[13] cancer cell lines monocyte cell line[24] colon cancer specimens modulates signaling kinetics expressing c-myc hif-1α mrna

Questions {❓}

• Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

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