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Title[redir]:
miR-874 functions as a tumor suppressor by inhibiting angiogenesis through STAT3/VEGF-A pathway in gastric cancer - PMC
Description:
MicroRNAs are endogenously expressed, small non-coding RNAs that regulate gene expression by targeting mRNAs for translational repression or degradation. Our previous studies indicated that miR-874 played a suppressive role in gastric cancer (GC) ...
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Keywords {🔍}
stat, cells, expression, doi, angiogenesis, tumor, vegfa, cell, cancer, levels, pubmed, google, scholar, tissues, protein, gastric, sgc, pmc, migration, ags, proliferation, invasion, huvecs, group, article, human, fig, targeting, results, compared, usa, inhibitor, free, growth, utr, lines, control, premir, analysis, shown, normal, assay, medium, mirnc, wang, assays, target, increased, huvec, figs,
Topics {✒️}
hrp-polymer-conjugated secondary antibody pik3c2alpha/akt/hif-1alpha pathway hrp-conjugated anti-mouse ags-pre-mir-874 stable cells pmc beta search firefly fluorescence/renilla fluorescence sds–polyacrylamide gel electrophoresis 12 μg pgl3-wt-stat3 ags-pre-mir-874-transfected group dual-luciferase reporter assay long-term survival rate tumour-suppressive microrna-874 contributes increases micro-vessel density ags-pre-mir-874 cells compared pre-existing blood vessels nanjing medical university inverted phase-contrast microscope sgc-7901-mir-874-inhibitor cells compared microrna-26a inhibits angiogenesis mir-874-sponge inhibitor vector supplementary materials oncotarget-06-1605-s001 mir-874-pre-microrna vector mir-874 inhibitor/pre-mir-874 mir-874 inhibitor-treated group mir-874-inhibitor-transfected cells pre-mir-874-transfected cells supplementary figure oncotarget-06-1605-s001 ags-pre-mir-874 cells license information pmcid mir-874-inhibitor+stat3-shcontrol sgc-7901-mir-874-inhibitor cells renilla luciferase activities pre-mir-874+lv-nc mir-874-inhibitor+stat3-shrna pre-mir-874+lv-stat3 ags-pre-mir-874 decreased stable cell lines luciferase reporter assay specific primary antibodies scrambled lentiviral construct target-specific reverse transcription human gastric cancer green fluorescent protein relative luciferase activity intestinal ischemic injury advanced gastric cancer cell-staining intensity cell physiol biochem 1 mg/ml matrigel primary gc tissues
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