
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Delivery of siRNA Therapeutics: Barriers and Carriers - PMC
Description:
RNA interference is a naturally occurring endogenous regulatory process where short double-stranded RNA causes sequence-specific posttranscriptional gene silencing. Small interference RNA (siRNA) represents a promising therapeutic strategy. Clinical ...
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Keywords {🔍}
sirna, doi, pubmed, google, scholar, delivery, gene, carriers, cells, pmc, rna, silencing, drug, cationic, article, free, target, tumor, nanoparticles, therapeutics, systemic, injection, surface, mrna, vivo, intravenous, cell, targeting, barriers, small, rnai, transfection, dendrimers, protein, cancer, nature, rev, degradation, release, deliv, specific, shrna, transport, size, solid, tumors, adv, jaddr, clinical, properties,
Topics {✒️}
deliver small-molecular-weight compounds abolished formalin-induced pain cell-penetrating peptides modified �cationic cell-penetrating peptides” liver-directed aav-encoded shrna sirna targeting c-myc age-related macular degeneration polymer-based vesicular shells cyclodextrin-based supramolecular architectures luteinizing hormone-releasing hormone respiratory syncytial virus cyclodextrin polymer-based nanoparticle transfect hiv-infected cd4 envelope-negative b16 cells rna-induced silencing complex gu-rich sequence motifs lipid-based sirna delivery lipid-based systemic delivery lipid-based sirna carriers a10-plk1 chimera targeting high-density amino groups short double-stranded rna short plasma half-life pmc beta search rna-interference-based therapeutics precise core–shell nanostructures cationic oligopeptide-mediated delivery hiv-infected jurkat cells producing gene-specific inhibition endosome–lysosome degradation axis optimized alpha-cyclodextrin conjugate target-independent angiogenesis suppression cell-penetrating peptide cell-specific targeting ligands induce sequence-specific silencing post-transcriptional gene silencing rnai-mediated gene-targeting pressure-driven convective flow sirna-mediated gene silencing phase iib n-protein prostate-specific membrane antigen single-strand rna molecule interferon-alpha/beta activation liposome-entrapped proteins injected peptide transduction domains lipid-based carriers rnai-mediated gene silencing dendrimer-mediated intracellular uptake hiv-1 envelope yielded cell type-specific delivery
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- How much does https://scholar.google.com/scholar_lookup?journal=Proc%20Natl%20Acad%20Sci%20USA&title=Impact%20of%20tumor-specific%20targeting%20on%20the%20biodistribution%20and%20efficacy%20of%20siRNA%20nanoparticles%20measured%20by%20multimodality%20in%20vivo%20imaging&author=DW%20Bartlett&author=H%20Su&author=IJ%20Hildebrandt&author=WA%20Weber&author=ME%20Davis&volume=104&issue=39&publication_year=2007&pages=15549-54&pmid=17875985&doi=10.1073/pnas.0707461104& bring in each month?
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- What's https://scholar.google.com/scholar_lookup?journal=Proc%20Natl%20Acad%20Sci%20USA&title=Administration%20in%20non-human%20primates%20of%20escalating%20intravenous%20doses%20of%20targeted%20nanoparticles%20containing%20ribonucleotide%20reductase%20subunit%20M2%20siRNA&author=JD%20Heidel&author=Z%20Yu&author=JY%20Liu&author=SM%20Rele&author=Y%20Liang&volume=104&issue=14&publication_year=2007&pages=5715-21&pmid=17379663&doi=10.1073/pnas.0701458104&'s gross income?
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