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NATURE . COM {}

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  6. How Much Does Nature.com Make
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We are analyzing https://www.nature.com/articles/s41575-024-00914-3.

Title:
The changing metabolic landscape of bile acids – keys to metabolism and immune regulation | Nature Reviews Gastroenterology & Hepatology
Description:
Bile acids regulate nutrient absorption and mitochondrial function, they establish and maintain gut microbial community composition and mediate inflammation, and they serve as signalling molecules that regulate appetite and energy homeostasis. The observation that there are hundreds of bile acids, especially many amidated bile acids, necessitates a revision of many of the classical descriptions of bile acids and bile acid enzyme functions. For example, bile salt hydrolases also have transferase activity. There are now hundreds of known modifications to bile acids and thousands of bile acid-associated genes, especially when including the microbiome, distributed throughout the human body (for example, there are >2,400 bile salt hydrolases alone). The fact that so much of our genetic and small-molecule repertoire, in both amount and diversity, is dedicated to bile acid function highlights the centrality of bile acids as key regulators of metabolism and immune homeostasis, which is, in large part, communicated via the gut microbiome. Bile acids have important roles in human metabolism and immune regulation. In this Perspective, Dorrestein and colleagues discuss the technologies and data science-related approaches that are improving our understanding of the diversity of bile acids and their multifaceted roles.
Website Age:
30 years and 10 months (reg. 1994-08-11).

Matching Content Categories {📚}

  • Education
  • Science
  • Health & Fitness

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌆 Monumental Traffic: 20M - 50M visitors per month


Based on our best estimate, this website will receive around 42,194,993 visitors per month in the current month.

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How Does Nature.com Make Money? {💸}


Display Ads {🎯}


The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.

Ads are managed by yourbow.com. Particular relationships are as follows:

Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.com

Reseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.com

How Much Does Nature.com Make? {💰}


Display Ads {🎯}

$531,700 per month
Estimations show Nature.com's display ad online revenue falls between $354,480 and $974,820 per month.

Keywords {🔍}

pubmed, article, google, scholar, cas, bile, central, acid, acids, gut, nature, nat, metabolism, human, microbiota, res, sci, lipid, microbiome, cell, chem, receptor, usa, mass, metabolic, disease, microbial, data, salt, biol, intestinal, microbiol, spectrometry, wang, mol, metabolites, content, liver, med, analysis, identification, conjugates, proc, natl, acad, cells, metabolomics, access, host, role,

Topics {✒️}

privacy policy nature portfolio journals 4-seco-12α-hydroxy-5β-cholan-3 nature portfolio data-independent ms/ms deconvolution gas-liquid chromatography-mass spectrometry advertising amino acid n-acyltransferase social media lipid research smith–lemli–opitz syndrome research progress reduce graft-versus-host disease liquid chromatography-mass spectrometry bile-acid-mediated decrease spectral libraries gas chromatography-mass spectrometry polycystic ovary syndrome microbiota-gut-brain-liver axis research 3β-hydroxy bile acids org/data/structure/download scientific reprints hepatic cholesterol 7ɑ-hydroxylase human ntn-hydrolase superfamily bile acid n-acetylglucosaminidation 6α-hydroxy bile acids short-chain fatty acids 7α-hydroxysteroid dehydratase hsh2 chronic fatigue syndrome nuclear receptors sxr/pxr n-acyl glycyltaurine conjugate alkaloid-sequestering poison frogs gut microbiome-linked metabolites chemical language microbiota-derived bile acids cross-sectional karmen study mass spectrometry data molecular-formula-oriented method extracellular matrix-related genes microbial bile-acid conjugates van der hooft amine-conjugated bile acids universal language positive/negative ion-switching publishing agreement high resolution lc/ms 7α-hydroxyl bile salts high-confidence structural annotation

Questions {❓}

  • Biotransformation of waste bile acids: a new possible sustainable approach to anti-fungal molecules for crop plant bioprotection?
  • Cholesterol metabolism pathways – are the intermediates more important than the products?
  • Middle-distance running acutely influences the concentration and composition of serum bile acids: potential implications for cancer risk?
  • Targeting the gut-skin axis – probiotics as new tools for skin disorder management?
  • Taurine: a conditionally essential amino acid in humans?

Schema {🗺️}

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               type:PostalAddress
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            name:University of California San Diego
            address:
               name:Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, USA
               type:PostalAddress
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      email:[email protected]
PostalAddress:
      name:Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, USA
      name:Department of Pediatrics, University of California San Diego School of Medicine, La Jolla, USA
      name:Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, USA
      name:Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, USA
      name:Department of Medicine, University of California San Diego, San Diego, USA
      name:Department of Pediatrics, University of California San Diego School of Medicine, La Jolla, USA
      name:Center for Microbiome Innovation, University of California San Diego, La Jolla, USA
      name:Department of Computer Science and Engineering, University of California San Diego, La Jolla, USA
      name:Department of Bioengineering, University of California San Diego, La Jolla, USA
      name:Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, USA
      name:Center for Microbiome Innovation, University of California San Diego, La Jolla, USA
      name:Department of Pharmacology, University of California San Diego, La Jolla, USA
      name:Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, USA
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