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Title:
The impact of mass drug administration of antibiotics on the gut microbiota of target populations | Infectious Diseases of Poverty
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Antibiotics have become a mainstay of healthcare in the past century due to their activity against pathogens. This manuscript reviews the impact of antibiotic use on the intestinal microbiota in the context of mass drug administration (MDA). The importance of the gut microbiota to human metabolism and physiology is now well established, and antibiotic exposure may impact host health via collateral effects on the microbiota and its functions. To gain further insight into how gut microbiota respond to antibiotic perturbation and the implications for public health, factors that influence the impact of antibiotic exposure on the microbiota, potential health outcomes of antibiotic-induced microbiota alterations, and strategies that have the potential to ameliorate these wider antibiotic-associated microbiota perturbations are also reviewed. Graphical Abstract
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Keywords {🔍}
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Topics {✒️}
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Questions {❓}
- Antimicrobial use: A risk factor or a protective factor for acquiring campylobacteriosis?
- Can breastfeeding protect against antimicrobial resistance?
- Do antibiotics cause obesity through long-term alterations in the gut microbiome?
- Do probiotics during in-hospital antibiotic treatment prevent colonization of gut microbiota with multi-drug-resistant bacteria?
- Do symbiotic bacteria subvert host immunity?
- Does the use of antibiotics in early childhood increase the risk of asthma and allergic disease?
- Group B streptococcal disease worldwide for pregnant women, stillbirths, and children: why, what, and how to undertake estimates?
- The hygiene hypothesisi revised: Is the rising frequency of allergy due to changes in rising the intestinal flora?
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headline:The impact of mass drug administration of antibiotics on the gut microbiota of target populations
description:Antibiotics have become a mainstay of healthcare in the past century due to their activity against pathogens. This manuscript reviews the impact of antibiotic use on the intestinal microbiota in the context of mass drug administration (MDA). The importance of the gut microbiota to human metabolism and physiology is now well established, and antibiotic exposure may impact host health via collateral effects on the microbiota and its functions. To gain further insight into how gut microbiota respond to antibiotic perturbation and the implications for public health, factors that influence the impact of antibiotic exposure on the microbiota, potential health outcomes of antibiotic-induced microbiota alterations, and strategies that have the potential to ameliorate these wider antibiotic-associated microbiota perturbations are also reviewed.
datePublished:2022-06-30T00:00:00Z
dateModified:2022-06-30T00:00:00Z
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Antibiotics
Mass drug administration
Microbiota
Microbiome
Infectious Diseases
Tropical Medicine
Public Health
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headline:The impact of mass drug administration of antibiotics on the gut microbiota of target populations
description:Antibiotics have become a mainstay of healthcare in the past century due to their activity against pathogens. This manuscript reviews the impact of antibiotic use on the intestinal microbiota in the context of mass drug administration (MDA). The importance of the gut microbiota to human metabolism and physiology is now well established, and antibiotic exposure may impact host health via collateral effects on the microbiota and its functions. To gain further insight into how gut microbiota respond to antibiotic perturbation and the implications for public health, factors that influence the impact of antibiotic exposure on the microbiota, potential health outcomes of antibiotic-induced microbiota alterations, and strategies that have the potential to ameliorate these wider antibiotic-associated microbiota perturbations are also reviewed.
datePublished:2022-06-30T00:00:00Z
dateModified:2022-06-30T00:00:00Z
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Mass drug administration
Microbiota
Microbiome
Infectious Diseases
Tropical Medicine
Public Health
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