
NCBI . NLM . NIH . GOV {
}
Title[redir]:
A Bacterial Bile Acid Metabolite Modulates Treg Activity through the Nuclear Hormone Receptor NR4A1 - PMC
Description:
Bile acids act as signaling molecules that regulate immune homeostasis, including the differentiation of CD4+ T cells into distinct T cell subsets. The bile acid metabolite isoallolithocholic acid (isoalloLCA) enhances the differentiation of ...
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Keywords {🔍}
isoallolca, google, scholar, doi, pubmed, acid, cells, bile, nra, atcc, gut, pmc, article, free, data, figure, bacteria, gene, cell, treg, oxolca, human, bacterial, foxp, dsm, merdae, acids, genes, differentiation, analysis, cluster, mice, hours, bacteroides, αreductase, shown, production, βhsdh, group, bacteroidetes, samples, table, βreductase, atacseq, ibd, performed, dorei, reads, strains, produce,
Topics {✒️}
recombinant dna pnbu2_erm-tetr-p1t_dp-gh023 org/packages/release/bioc/html/limma org/packages/release/bioc/html/clusterprofiler org/packages/release/bioc/html/deseq2 population-scale meta-omics studies ice-cold phosphate-buffered saline specific pathogen-free conditions proposed intermediate 3-oxo-δ4-lca intermediate metabolites 3-oxo-δ4-lca [google scholar] lloyd-price target compound 3-oxo-δ4-lca germ-free b6 mice dual-luciferase reporter kit n-terminal his6 tag β-nicotinamide adenine dinucleotide [google scholar] funabashi treg cell-modulating activity 3-oxo-δ4-lithocholic acid host-derived bile acids pmc beta search iccb-longwood screening facility [google scholar] kaminski bacdor_03091 converted 3-oxo-δ4-lca x-axis tick labels targeting bile-acid signalling bile salt hydrolase short-chain fatty acids intermediates 3-oxo-δ4-lca atac-seq peak sets bacteroides dorei p6-h5 treg-enhancing bile acid regulatory t-cell fate identify atac-seq peaks microbiota-derived bile acids representative uplc-ms traces putative 17β-hsdh inserted produce iso-bile acids parabacteroides merdae p1-d8 io/recipes/bowtie2/readme real-time pcr carried io/recipes/cutadapt/readme bacteroides vulgatus p6-d10 monocolonized germ-free foxp3 promoter-firefly luciferase real-time pcr analyses bile acid-activated receptors microbiota-inspired therapies targeting fast gapped-read alignment real-time pcr analysis molecular biology-grade dmso
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