We are analyzing https://link.springer.com/article/10.1007/s12177-009-9030-x.

Title:
Bile acids in treatment of ocular disease | Journal of Ocular Biology, Diseases, and Informatics
Description:
Bear bile has been included in Asian pharmacopeias for thousands of years in treatment of several diseases, ranging from sore throat to hemorrhoids. The hydrophilic bile acids tauroursodeoxycholic acid (TUDCA) and ursodeoxycholic acid (UDCA) are the major bile acids of bear bile. Both of these are available as synthetic formulations and are approved by the health administrations of several countries for treatment of cirrhosis and gallstones. This review briefly covers the use of bear bile in Traditional Chinese Medicine, bile acid physiology, approved use of UDCA and TUDCA in Western medicine, and recent research exploring their neuroprotective properties, including in models of ocular disease.
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Keywords {🔍}

tudca, google, scholar, acid, pubmed, bile, article, cas, mice, treatment, udca, retinal, ursodeoxycholic, acids, apoptosis, bear, degeneration, liver, tauroursodeoxycholic, effect, disease, cell, photoreceptor, models, mouse, cells, biliary, rat, rats, rodrigues, fig, injury, tudcatreated, outer, layer, retina, sci, effects, sections, mitochondrial, vehicletreated, onl, image, patients, nuclear, steer, light, loss, days, vis,

Topics {✒️}

bright-light-exposure-induced massive apoptosis bright-light-exposed vehicle-treated mice bright-light-exposed tudca-treated mice dark-adapted b-waves maintained vehicle dim-light-exposed vehicle-injected pi3k/akt dependent pathway article download pdf bright-light-exposed vehicle-injected immobilized dual-enzymatic system modulating pkcalpha-ezrin pathway bright-light exposed tudca-injected dark-adapted a-waves cisplatin-induced sensory neuropathy e2f-1/p53/bax pathway 500 mg/kg body weight axon-mediated gene transfer traditional chinese medicine average b-wave amplitude endoplasmic reticulum stress dark-adapted a-wave adult c57/bl6 mice org/eng/app/index rota-rod sensorimotor task enteral donor pre-treatment vehicle-treated retinas showed obstructive jaundice-rat model warm ischemia-reperfusion injury post-ischemic mitochondrial injury vehicle-treated mice exposed tudca-treated rats compared dim-light-exposed mice oxidative stress models 15 days post-light exposure tudca-treated mice exposed taurine-conjugated ursodeoxycholic acid wild-type retinal morphology apoptotic cell death biliary epithelial cells spinal cord injury tudca-injected mice exposed vehicle-treated rd10 mice glutamate-induced apoptosis microglial cell line ursodeoxycholic acid-induced privacy choices/manage cookies ganglion cell layer ischemia-reperfusion liver injury hydrophilic bile acids segment/outer segment bile acid physiology

Schema {🗺️}

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         description:Bear bile has been included in Asian pharmacopeias for thousands of years in treatment of several diseases, ranging from sore throat to hemorrhoids. The hydrophilic bile acids tauroursodeoxycholic acid (TUDCA) and ursodeoxycholic acid (UDCA) are the major bile acids of bear bile. Both of these are available as synthetic formulations and are approved by the health administrations of several countries for treatment of cirrhosis and gallstones. This review briefly covers the use of bear bile in Traditional Chinese Medicine, bile acid physiology, approved use of UDCA and TUDCA in Western medicine, and recent research exploring their neuroprotective properties, including in models of ocular disease.
         datePublished:2009-08-27T00:00:00Z
         dateModified:2009-08-27T00:00:00Z
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            Apoptosis
            Retinal degeneration
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            Traditional Chinese medicine
            Tauroursodeoxycholic acid
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            UDCA
            Ophthalmology
            Health Informatics
            Neurology
            Medicinal Chemistry
            Neurobiology
            Neurochemistry
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      headline:Bile acids in treatment of ocular disease
      description:Bear bile has been included in Asian pharmacopeias for thousands of years in treatment of several diseases, ranging from sore throat to hemorrhoids. The hydrophilic bile acids tauroursodeoxycholic acid (TUDCA) and ursodeoxycholic acid (UDCA) are the major bile acids of bear bile. Both of these are available as synthetic formulations and are approved by the health administrations of several countries for treatment of cirrhosis and gallstones. This review briefly covers the use of bear bile in Traditional Chinese Medicine, bile acid physiology, approved use of UDCA and TUDCA in Western medicine, and recent research exploring their neuroprotective properties, including in models of ocular disease.
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         Apoptosis
         Retinal degeneration
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         Traditional Chinese medicine
         Tauroursodeoxycholic acid
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         UDCA
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         Health Informatics
         Neurology
         Medicinal Chemistry
         Neurobiology
         Neurochemistry
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