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keap, cells, ferroptosis, cancer, fsp, pubmed, cell, fig, article, lung, google, scholar, cas, data, nrf, supplementary, central, lipid, tumor, levels, gpx, expression, peroxidation, mutant, nature, coq, cba, cancers, deficient, rsl, treatment, death, tumors, study, deletion, target, xray, slca, fin, resistance, survival, deficiency, irradiation, analysis, protein, fins, radiation, class, source, pathway,

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nature portfolio privacy policy middle line represents advertising apoptosis inhibitor z-vad-fmk fsp1 promoter-luciferase activities p62-keap1-nrf2 pathway protects depmap data portal reprints foxo-bnip3 axis exerts perform real-time pcr cancer genome atlas japan hek-293t cells treated cancer research communities cystine transporter slc7a11/xct keap1 deficiency-induced resistance n-terminal v5 tag thermofisher scientific esmo open 5 kopchick research award rt-induced lipid peroxidation slc7a11-keap1 dko cells rt-induced cell death21 cell culture media lentivirus vector plx304-blasticidin necroptosis inhibitor necrostatin-1s gpx4-keap1 dko cells org/portal/ p53-inducible gene downregulated bi-dimensional tumor measurements remove serum-derived coq institutional research fund 100 mm tris-hcl ph8 cold dmem media 100 μm tert-butyl-hydroquinone molina das & boyi gan tsc-mtor signaling pathways lncrna nbr2 engages glutathione-independent ferroptosis suppressor patient-derived xenograft tumors rsl3-induced cell death nature 575 nature 593 nature 520 nature 585 nature 572 nature 547 nature 551 nature 489

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• Unsolved mysteries: how does lipid peroxidation cause ferroptosis?

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            address:
               name:Kadmon Corporation, LLC, New York, USA
               type:PostalAddress
            type:Organization
      name:Jiejun Shi
      url:http://orcid.org/0000-0001-9777-1183
      affiliation:
            name:University of California
            address:
               name:Division of Computational Biomedicine, Department of Biological Chemistry, School of Medicine, University of California, Irvine, USA
               type:PostalAddress
            type:Organization
      name:Xiaoguang Liu
      url:http://orcid.org/0000-0001-6977-5128
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:Amber Horbath
      url:http://orcid.org/0000-0003-1482-8637
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:Molina Das
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
      name:Wei Li
      url:http://orcid.org/0000-0001-9931-5990
      affiliation:
            name:University of California
            address:
               name:Division of Computational Biomedicine, Department of Biological Chemistry, School of Medicine, University of California, Irvine, USA
               type:PostalAddress
            type:Organization
      name:Masha V. Poyurovsky
      affiliation:
            name:Kadmon Corporation, LLC
            address:
               name:Kadmon Corporation, LLC, New York, USA
               type:PostalAddress
            type:Organization
      name:Kellen Olszewski
      affiliation:
            name:Kadmon Corporation, LLC
            address:
               name:Kadmon Corporation, LLC, New York, USA
               type:PostalAddress
            type:Organization
            name:The Barer Institute
            address:
               name:The Barer Institute, Philadelphia, USA
               type:PostalAddress
            type:Organization
      name:Boyi Gan
      url:http://orcid.org/0000-0001-8884-6040
      affiliation:
            name:The University of Texas MD Anderson Cancer Center
            address:
               name:Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
               type:PostalAddress
            type:Organization
            name:The University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences
            address:
               name:The University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:The University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, USA
      name:Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Kadmon Corporation, LLC, New York, USA
      name:Division of Computational Biomedicine, Department of Biological Chemistry, School of Medicine, University of California, Irvine, USA
      name:Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:Division of Computational Biomedicine, Department of Biological Chemistry, School of Medicine, University of California, Irvine, USA
      name:Kadmon Corporation, LLC, New York, USA
      name:Kadmon Corporation, LLC, New York, USA
      name:The Barer Institute, Philadelphia, USA
      name:Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA
      name:The University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, USA

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