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Keywords {🔍}

ferroptosis, cancer, cell, cells, doi, fig, lipid, peroxidation, tumor, slca, acsl, expression, pubmed, irinduced, google, scholar, supplementary, information, treatment, pmc, article, staining, free, calculated, gpx, bars, values, means, fins, survival, exposure, error, independent, sulfasalazine, unpaired, students, ttest, radiotherapy, repeats, twotailed, response, radioresistance, ferrostatin, lines, data, hne, death, samples, radiation, induces,

Topics {✒️}

ros scavenger n-acetyl-l-cysteine 5 mm n-acetyl-l-cysteine long-chain fatty-acid-coenzyme cystine/glutamate transporter-deficient mice foxo-bnip3 axis exerts high-energy ionizing radiation apoptosis inhibitor z-vad-fmk keap1-mutant lung cancer glioma-induced brain edema unstable carbon-centered radicals keap1-mutant lung cancers tab patient-derived xenograft cold phosphate-buffered saline form fatty-acid radicals bar graph showing author contributions pmc beta search ir-induced h2ax phosphorylation equation volume = length × width2 × 1/2 5 μm z-vad-fmk nod scid gamma ir-induced lipid peroxidation ir-induced dna damage ir-induced cell death xenograft tumors derived 4-hne mild/moderate group tsc-mtor signaling pathways ir-induced tumor suppression evidence-based clinical guidelines necroptosis inhibitor necrostatin-1s quantitative real-time pcr dampens ir-induced ferroptosis post-radiotherapy tumor samples mild/moderate 4-hne staining qrt-pcr qrt-pcr lncrna nbr2 engages anti-phospho-histone h2a converting pufa-pl-ooh ferroptosis inhibition-mediated radioresistance drives pufa-pl peroxidation pre-radiotherapy tumor samples slc7a11-mediated ferroptosis inhibition master transcription factor renal tumor growth generate acsl4 knockout significantly sensitizes tumors z-vad-fmk competing interests slc7a11-expressing h1299 cells inhibiting ir-induced ferroptosis

Questions {❓}

• Unsolved mysteries: How does lipid peroxidation cause ferroptosis?

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