
NCBI . NLM . NIH . GOV {
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Title[redir]:
βCysteine depletion induces pancreatic tumor ferroptosis in miceβ - PMC
Description:
Ferroptosis is a form of cell death resulting from the catastrophic accumulation of lipid reactive oxygen species (ROS). Oncogenic signaling elevates lipid ROS production in many tumor types and is counteracted by metabolites derived from the amino ...
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Keywords {π}
fig, scholar, google, doi, ferroptosis, pubmed, pmc, article, pdac, pancreatic, cell, free, cells, cancer, mice, pdf, figure, nihmssupplementfigurespdf, cysteine, tumors, lipid, cysteinase, cystine, tumor, hours, treated, human, data, kpfsr, coa, kpc, depletion, death, growth, system, lines, inhibition, expression, survival, slca, viability, ductal, ike, vehicle, nlm, induces, gsh, gene, treatment, observed,
Topics {βοΈ}
figure s13 nihms1643619-supplement-figure_s13 figure s1 nihms1643619-supplement-figure_s1 figure s3 nihms1643619-supplement-figure_s3 supplementary text nihms1643619-supplement-supplementary_text figure s4 nihms1643619-supplement-figure_s4 figure s7 nihms1643619-supplement-figure_s7 figure s9 nihms1643619-supplement-figure_s9 figure s10 nihms1643619-supplement-figure_s10 figure s11 nihms1643619-supplement-figure_s11 figure s12 nihms1643619-supplement-figure_s12 figure s2 nihms1643619-supplement-figure_s2 figure s6 nihms1643619-supplement-figure_s6 figure s5 nihms1643619-supplement-figure_s5 figure s8 nihms1643619-supplement-figure_s8 cystine/glutamate transporter-deficient mice poly-unsaturated fatty acids phic31 site-specific recombination nih grant u24-dk097153 african-centric s47 variant erastin-treated ht-1080 cells induced tumor-selective ferroptosis high-density dna microarrays model-based background adjustment pmc beta search fluorescent probe c11-bodipy tamoxifen-treated kpfsr epithelia 1mm n-acetyl cysteine lc-tof-ms analysis tamoxifen-treated kpfsr tumors tamoxifen-treated kpfsr mice membrane-permeable analog liquid chromatography time tumor-selective cysteine dependency inase-treated tumors revealed historical vehicle-treated controls table s1 reactive oxygen species cystine-free media [google scholar] 23 [google scholar] 32 [google scholar] 38 [google scholar] 39 ike-sensitive pdac lines inase-treated kpc tumors prevented ike-induced ferroptosis cell permeable analog junior scholar award kimmel scholar award restored protein expression amino acid cysteine
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- What's https://www.usa.gov/'s gross income?
Analytics and Tracking {π}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {π}
- Foundation
- jQuery
- jQuery module (jquery-3.6.0)
Emails and Hosting {βοΈ}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {π¦}
- Ncbi