PMC . NCBI . NLM . NIH . GOV {
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We are analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC2212780/.
Title:
The role of mitochondria in protection of the heart by preconditioning - PMC
Description:
A prolonged period of ischaemia followed by reperfusion irreversibly damages the heart. Such reperfusion injury (RI) involves opening of the mitochondrial permeability transition pore (MPTP) under the conditions of calcium overload and oxidative ...
Website Age:
27 years and 8 months (reg. 1997-10-02).
Title:
The role of mitochondria in protection of the heart by preconditioning - PMC
Description:
A prolonged period of ischaemia followed by reperfusion irreversibly damages the heart. Such reperfusion injury (RI) involves opening of the mitochondrial permeability transition pore (MPTP) under the conditions of calcium overload and oxidative ...
Website Age:
27 years and 8 months (reg. 1997-10-02).
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Keywords {🔍}
doi, mitochondrial, google, scholar, pubmed, mitochondria, preconditioning, reperfusion, opening, mptp, channel, heart, katp, ros, channels, role, matrix, ischaemia, membrane, res, free, hearts, protein, permeability, pore, isolated, cell, transition, injury, kinase, pmc, volume, inhibition, article, calcium, data, effects, rat, halestrap, production, protection, potassium, mechanism, increase, atp, phosphorylation, cardiac, biol, physiol, cardiovasc,
Topics {✒️}
tyr-d-ala-gly-phe-d-leu peptidyl-prolyl cis-trans isomerase peptidyl-prolyl cis-trans-isomerase k-atp-channel-openers-induced proton diazoxide/glibencamide-sensitive k-atp channels pre-ischemic p38-mapk activation long-chain acyl-coa esters diazoxide/5-hydroxydecanoatesensitive k-atp channel k-atp channel-independent targets n6o2′-dibutyryladenosine 3′5′-cyclic monophosphate voltage-dependent anion channel voltage-dependent anion channels potentiates chemotherapy-induced cytotoxicity pmc beta search atp-dependent potassium channels atp-dependent repair processes mitochondrial k-atp channel l-3-hydroxyacyl-coa dehydrogenase myocardial k-atp channels mitochondrial k-atp channels ischemic/reperfused rat heart—involvement branched-chain 2-oxoacid dehydrogenase cardiac k-atp channels real-time 2-photon imaging atp-sensitive potassium channel sarcolemmal k-atp channels atp-sensitive potassium channels opening mitochondrial k-atp calcium-activated potassium channel amp-activated protein kinase cardiac proteins s-thiolated delta-protein kinase immuno-gold electron microscopy glycogen synthase kinase-3 targeting nucleotide-requiring enzymes pkc-dependent insulin exocytosis potassium free medium recombinant adp/atp carrier 200 nm phorbol-12-myristate-13-acetate o-18-assisted p-31 nmr g-protein coupled receptors h2o2-induced cardiac dysfunction heterozygous connexin43-deficient mice pro-apoptotic factor bax mitochondrial adp/atp carrier potassium free media free radical scavenger mitochondrial-dependent cell death sensitive real-time measurement 5-hydroxydecanoate inhibits atp-sensitive
Questions {❓}
- Diazoxide induced cardioprotection: what comes first, KATP channels or reactive oxygen species?
- Does the mitochondrial permeability transition have a role in preconditioning?
- Dual role for the ADP/ATP translocator?
- Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning?
- Is there evidence for regulation by phosphorylation?
- Is there good evidence for mitochondrial K+ channels being involved in the protective mechanism of preconditioning?
- Mitochondria and preconditioning: a connexin connection?
- Mitochondrial ATP-dependent potassium channels: Novel effectors of cardioprotection?
- Mitochondrial modulation: reversible phosphorylation takes center stage?
- PTEN, the Achilles' heel of myocardial ischaemia/reperfusion injury?
- Paradoxical effect of ischemic preconditioning on ischemic contracture?
- Proposed mechanisms by which opening of mitochondrial K+ channels might protect hearts from ischaemia reperfusion injury?
- Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function?
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