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Title:
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death - PubMed
Description:
Mitochondria play an important role in energy production, Ca2+ homeostasis and cell death. In recent years, the role of the mitochondria in apoptotic and necrotic cell death has attracted much attention. In apoptosis and necrosis, the mitochondrial permeability transition (mPT), which leads to disru …
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Keywords {🔍}
doi, pmid, mitochondrial, death, cell, metabolism, mitochondria, role, mice, injury, cyclophilin, pmc, pathology, myocardial, cited, nature, permeability, transition, necrotic, apoptotic, hepatocytes, epub, free, article, articles, mesh, mar, apoptosis, mpt, protein, cypddeficient, reactive, oxygen, species, review, gene, calcium, cyclophilins, genetics, main, ncbi, abstract, similar, resources, shimizu, tsujimoto, necrosis, showed, pubmed, renal,
Topics {✒️}
ischaemia/reperfusion-induced cardiac injury hypoxia-ischemia injury reactive oxygen species ischemic rat hepatocytes main page content traumatic brain injury ischemic renal injury cypd-deficient mice showed cypd-deficient cells died cypd-deficient mice mnd2 mutant mice cypd-dependent mpt regulates books gene gene mitochondrial permeability transition cyclosporin a-sensitive mpt regulatory necrosis resources nature necrosis mesh keyword similar articles cited cypd-deficient mitochondria biochem res int united states government anticancer-targeted therapies front mol neurosci medgen nucleotide omim physiol renal physiol apoptotic cell death mitochondrial membranes mitochondrial dysfunction mitochondrial dynamics necrotic cell death similar articles role abstract schneider md cell death cardiotoxicity induced apoptotic death biomedical research apoptosis necrotic death knockout mitochondria hhs renal pathophysiology apoptotic stimuli kidney int linkout pubmed wordmark pubmed logo 12557154 cyclophilin
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