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Title:
The mitochondrial permeability transition from in vitro artifact to disease target - PubMed
Description:
The mitochondrial permeability transition pore is a high conductance channel whose opening leads to an increase of mitochondrial inner membrane permeability to solutes with molecular masses up to approximately 1500 Da. In this review we trace the rise of the permeability transition pore from the sta …
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Keywords {🔍}
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Topics {✒️}
drug-induced liver injury membrane permeability cardiac diseases mitochondrial permeability transition ischemia-reperfusion injury ischemia/reperfusion injury permeability transition pore blocks n-methyl-d-aspartate receptor inhibits mitochondrial complex mitochondrial connection mitochondrial permeability transition main page content united states government pore structure funding linkout free article erratum attenuates calcium-induced opening extramural research support literature sources similar articles cited review 18074637 review 18193649 review 18407825 review fabio di lisa high conductance channel novartis found symp biochim biophys acta basic res cardiol increased potassium conductance enhancing matrix volume promising therapeutic target calcium-independent phospholipase neonatal cardiac mitochondria discuss evidence indicating pharmacol exp ther mol cell biochem elizabeth blachly-dyson hhs opening leads elizabeth] abstract recent progress blachly-dyson pubmed wordmark pubmed logo subcell biochem mol sci blalchy-dyson elizabeth [corrected
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