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Title:
Ischaemic preconditioning inhibits opening of mitochondrial permeability transition pores in the reperfused rat heart - PubMed
Description:
Opening of the mitochondrial permeability transition pore (MPTP) is thought to be a critical event in mediating the damage to hearts that accompanies their reperfusion following prolonged ischaemia. Protection from reperfusion injury occurs if the prolonged ischaemic period is preceded by short isch โฆ
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Keywords {๐}
mitochondrial, transition, doi, opening, permeability, pmid, mptp, pore, pubmed, pmc, hearts, ipc, preconditioning, heart, reperfusion, injury, figure, epub, mitochondria, free, article, channels, metabolism, articles, mesh, ischaemic, clarke, halestrap, protection, cyclosporin, effects, myocardial, cardiovasc, res, pharmacology, main, ncbi, similar, cited, references, resources, jun, apr, rat, javadov, ischaemia, inhibition, perfusion, calcium, sanglifehrin,
Topics {โ๏ธ}
similar articles cited mitochondrial k-atp channels main page content mitochondrial transition pore risk-gsk-3ฮฒ-mptp pathway mitochondrial permeability transition mitochondrial transport resources comparative study mitochondrial adp/atp carrier mitochondrial [3h]dog entrapment mitigate storage/reperfusion injury glycogen synthase kinase-3beta decreased calcium overload ischemic preconditioning n-methyl-4-isoleucine cyclosporin permeability transition langendorff-perfused rat hearts affecting myocardial function reperfusion injury occurs myocardial preconditioning ischemia-reperfusion injury mesh keyword channels myocardial reperfusion short ischaemic periods preventing mptp opening induce mptp opening rat liver transplantation reperfusion injury mitochondrial abnormalities united states government 2-deoxy[3h]glucose improved haemodynamic function biochim biophys acta mol cell biochem arch med sci prolonged ischaemic period parodi-rullรกn rm ischaemic preconditioning sirt3 deficient hearts lactate dehydrogenase release ipc hearts occurred cited effects sanglifehrin mptp opening heart mitochondria isolated control mitochondria cns mitochondria
Questions {โ}
- Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning?
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