
PMC . NCBI . NLM . NIH . GOV {
}
Title:
CypDβ/β Hearts HaveAltered Levels of Proteins Involved in Krebs Cycle, Branch Chain Amino Acid Degradation and Pyruvate Metabolism - PMC
Description:
Cyclophilin D (CypD) is a mitochondrial chaperone that has been shown to regulate the mitochondrial permeability transition pore (MPTP). MPTP opening is a major determinant of mitochondrial dysfunction and cardiomyocyte death during ...
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27 years and 8 months (reg. 1997-10-02).
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Keywords {π}
mitochondrial, cypd, doi, protein, hearts, mice, mitochondria, dehydrogenase, google, scholar, pubmed, itraq, found, pmc, figure, heart, activity, free, subunit, analysis, pathways, decrease, proteins, acyl, article, succinate, min, acid, carnitine, male, performed, nadh, mptp, metabolic, buffer, data, oxidation, chain, metabolism, cyclophilin, isolated, differences, higher, shown, permeability, transition, increased, table, inhibition, transfer,
Topics {βοΈ}
long-chain-fatty-acid--coa ligase 1 peptidyl-prolyl cis-trans-isomerase 2-trans-enoyl-coa isomerase data-dependent hcd-ms2 scans include methylcrotonoyl-coa carboxylase maldi-tof/tof instrument dihydrolipoyllysine-residue succinyltransferase component dihydrolipoyllysine-residue acetyltransferase component thioredoxin-dependent peroxide reductase water-filled latex balloon thiol-specific antioxidant protein ventricular/cardiac muscle isoform nadp-dependent malic enzyme pmc beta search high-energy collision dissociation acetaminophen-induced oxidant stress ischemia/reperfusion-induced damage pmc copyright notice enoyl-coa hydratase domain succinate versus glutamate-malate ltq-orbitrap velos settings cross-stain analysis function mitochondrial f1-atpase activity lc-ms/ms analysis permeability transition pore ice-cold krebs-heinseleit carnitine/acyl carnitine carrier reduced Ξ±-ketoglutarate efflux d-2-hydroxyglutarate dehydrogenase malate-aspartate shuttle capacity ca2+-activated mitochondrial dehydrogenases ms/ms mass range generate free carnitine agilent hp1100 system pyruvate dehydrogenase complex mitochondrial free carnitine oxidase subunit 6b1 mitochondrial permeability transition increased Ξ±-ketoglutarate levels free radic res electron transport chain [google scholar] 26 electron transfer flavoprotein etf-ubiquinone dehydrogenase data-dependent mode enoyl-coa hydratase enoyl coa hydratase publisher site pdf Ξ±-ketoglutarate dehydrogenase license information pmcid
Questions {β}
- What is the mitochondrial permeability transition pore?
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