
PUBMED . NCBI . NLM . NIH . GOV {
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Title:
CypD(-/-) hearts have altered levels of proteins involved in Krebs cycle, branch chain amino acid degradation and pyruvate metabolism - PubMed
Description:
Cyclophilin D (CypD) is a mitochondrial chaperone that has been shown to regulate the mitochondrial permeability transition pore (MPTP). MPTP opening is a major determinant of mitochondrial dysfunction and cardiomyocyte death during ischemia/reperfusion (I/R) injury. Mice lacking CypD have been wide …
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Keywords {🔍}
mitochondrial, cyclophilin, doi, pmc, metabolism, pmid, permeability, cypd, transition, pubmed, pore, free, article, epub, hearts, acid, mice, figure, proteins, metabolic, articles, mesh, cell, mar, dec, amino, mptp, analysis, found, pathways, sep, main, ncbi, figures, similar, cited, references, resources, jyjmcc, levels, cycle, chain, nguyen, murphy, death, injury, study, proteomics, protein, electron,
Topics {✒️}
branched-chain peptidyl-prolyl isomerase peptidyl-prolyl cis-trans-isomerase main page content similar articles cited electron transport chain mitochondrial permeability transition united states government pyruvate metabolism proteins involved stress-induced dynamic regulation mitochondrial pore modulates mitochondrial acetylome fetal mouse hearts distinct mitochondrial cyclophilin funding linkout ischemia/reperfusion mesh keyword resources mice lacking cypd mitochondrial chaperone mitochondrial dysfunction mitochondrial ca curr pharm des increases enzyme activity mitochondrial stat3 moderates platelet adhesion biochim biophys acta n-terminal sequencing mol cell cardiol top canonical pathways present study aimed proximal tubule cyclophilin krebs cycle electron transfer flavoprotein apoptotic cell death figures molecular nature examine protein cited medgen protein found decreased levels pubmed tanveer pubmed nakagawa pubmed show pubmed wordmark pubmed logo elsevier mice di lisa hhs
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