PUBMED . NCBI . NLM . NIH . GOV {
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Title:
Cyclophilin D interacts with Bcl2 and exerts an anti-apoptotic effect - PubMed
Description:
Cyclophilin D (CypD) is a mitochondrial immunophilin and a key positive regulator of the mitochondrial permeability transition (MPT). Several reports have shown that CypD is overexpressed in various tumors, where it has an anti-apoptotic effect. Because the MPT is a cell death-inducing phenomenon, w …
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Keywords {🔍}
doi, pmid, pmc, cypd, cyclophilin, pubmed, effect, mitochondrial, mitochondria, free, article, permeability, transition, bcl, apoptosis, protein, apr, mpt, cell, release, cytochrome, figure, articles, mesh, biol, epub, antiapoptotic, zhang, main, ncbi, similar, cited, references, resources, chem, jbcm, interaction, function, cancer, cells, calcium, review, proteins, wang, research, nih, metabolism, gene, pubchem, hhs,
Topics {✒️}
main page content similar articles cited bcl-2 family proteins attenuates calcium-induced opening cell death-inducing phenomenon united states government chemical cross-linking method articles references dragovich mesh keyword mitochondrial permeability transition calcium-independent phospholipase anti-apoptotic effect roman pubchem substance grants funding linkout cell mol med mitochondrial protein cyclophilin resources nucleotide protein protein key apoptosis regulator extramural research support heat shock protein-90 intact cells function experiments confirm liver mitochondria cancer cells key positive regulator cell death curr pharm des skin wound healing oral lichen planus anti-apoptotic effect binding partners brain mitochondria calcium cell sensitivity adult human brain tbid-induced release mitochondria independent apoptosis progressing cited mitochondrial immunophilin hybrid assays pubmed wordmark pubmed logo protein observed hhs mitochondria biomedical research apoptosis mediated
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