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Title:
Regulation of tumor cell mitochondrial homeostasis by an organelle-specific Hsp90 chaperone network - PubMed
Description:
Molecular chaperones, especially members of the heat shock protein 90 (Hsp90) family, are thought to promote tumor cell survival, but this function is not well understood. Here, we show that mitochondria of tumor cells, but not most normal tissues, contain Hsp90 and its related molecule, TRAP-1. The …
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Keywords {🔍}
doi, hsp, pmid, cell, mitochondrial, protein, tumor, free, article, cancer, pmc, altieri, proteins, nih, states, articles, mesh, epub, review, physiology, main, ncbi, similar, cited, related, resources, oct, regulation, chaperone, plescia, dohi, molecular, chaperones, function, mitochondria, pubmed, shepherdin, gene, signaling, human, intracellular, benzoquinones, pharmacology, lactams, macrocyclic, hhsunited, hhs, page, content, access,
Topics {✒️}
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- Inhibition of the mitochondrial Hsp90 chaperone network: a novel, efficient treatment strategy for cancer?
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