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pubmed, article, google, scholar, cas, central, cell, cancer, methylation, nat, nature, dna, histone, epigenetic, mutations, cells, mol, chromatin, ezh, rna, biol, genet, rev, stem, med, human, leukemia, aging, gene, genes, res, authors, complex, regulation, therapy, myeloid, inhibition, blood, molecular, expression, development, science, genome, oncol, content, access, tet, methyltransferase, acute, protein,

Topics {✒️}

permissions reprints privacy policy nature portfolio journals editing dna methylation rna-polymerase-i-dedicated modification nature portfolio advertising cancer research dna double-strand breaks medical research g1/g2 cell-cycle phases swi/snf-mutant cancers depend social media editing open-label open questions language calm-af10-positive leukemias anti-tumour immunity controlled crispr-cas9 screen reveals prc2-mediated transcriptomic alterations a-dependent translation control alpha-ketoglutarate-dependent dioxygenases assemble cbx8-bcor complex integrated molecular meta-analysis h3k27m-mutant pediatric gliomas dna methylation-based biomarkers dna methylation-based measures baf-polycomb complex opposition gene-dosage compensation process dna-binding factors shape mycn-amplified neuroblastoma dependency triple-negative breast cancer refractory ini1-negative tumors age-dependent dna methylation information content polycomb-mediated repression required nucleosome-interacting proteins regulated peer review histone methyltransferase dot1/dot1l origin gene-expression status //tcga-data permissions epitranscriptome sequencing data meta-analysis predicting time springerlink instant access de novo methylation endogenous retroviral elements circulating tumor dna age-related clonal hematopoiesis

Questions {❓}

• Cancer genetics and epigenetics: two sides of the same coin?
• DNA methylation: superior or subordinate in the epigenetic hierarchy?
• Histone methylation: dynamic or static?
• Histone modification: cause or cog?

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