NCBI . NLM . NIH . GOV {
}
We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC3681809/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC3681809/. The analysis below is for the second page.
Title[redir]:
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation - PMC
Description:
The EZH2 histone methyltransferase is highly expressed in germinal center (GC) B-cells and targeted by somatic mutations in B-cell lymphomas. Here we find that EZH2 deletion or pharmacologic inhibition suppresses GC formation and functions in mice. ...
Title[redir]:
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation - PMC
Description:
The EZH2 histone methyltransferase is highly expressed in germinal center (GC) B-cells and targeted by somatic mutations in B-cell lymphomas. Here we find that EZH2 deletion or pharmacologic inhibition suppresses GC formation and functions in mice. ...
Matching Content Categories {📚}
- Science
- Education
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Content Management System {📝}
What CMS is ncbi.nlm.nih.gov built with?
Custom-built
No common CMS systems were detected on Ncbi.nlm.nih.gov, and no known web development framework was identified.
Traffic Estimate {📈}
What is the average monthly size of ncbi.nlm.nih.gov audience?
🌠 Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 6,694,437 visitors per month in the current month.
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How Does Ncbi.nlm.nih.gov Make Money? {💸}
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Keywords {🔍}
ezh, cells, figure, doi, genes, cell, mutant, bcells, bcell, gsk, mice, dlbcl, bivalent, hkme, scholar, differentiation, pubmed, google, expression, bcl, lymphoma, data, ezhyn, gene, gcb, pmc, mutations, phenotype, formation, lines, center, lymphomas, human, ezhyf, article, proliferation, induced, cancer, germinal, somatic, gcbdlbcl, free, histone, chipseq, specific, target, inhibitors, required, expressed, dlbcls,
Topics {✒️}
antigen-naïve b-cells present gl7+/fas+/b220+ gc b-cells frt-hygro-pa cassette downstream develop b-cell lymphomas gcb-dlbcl patient samples neoplastic-appearing b220+ b-cells gc b-cells exhibit performing high-throughput screening gc b-cell marker nitrophenyl-keyhole limpet hemocyanin loxp-flanked ezh2 allele pmc beta search follicular b-cell numbers retrovirus expressing gfp b-cell lymphomas arise impair b-cell differentiation b-cell differentiation showed human b-cell lymphomas collaborative trans-network grant transform b-cells affords gc b-cell differentiation gc b-cells upregulate gc b-cells suggested residual gc b-cells normal gc b-cells cancer cell abstract b-cell differentiation genes peri-cardiac soft tissue human gc b-cells ezh2-wt expressing cells gc b-cell phenotype reactive-appearing small lymphocytes incomplete cre-mediated excision gc b-cells originate sorted gc b-cells ezh2 chip-seq reads b-cell maturation function chip-seq density plot human gcb-dlbcl patients mutant ezh2 gcb-dlbcl combination chemo-immunotherapy regimens h3k27 chip-seq profiles lox-stop-lox cassette chip-seq showed enrichment gc b-cells concordant mature b-cells located transcriptional programs involved gc b-cells represent mrna-seq library preparation tissue-specific stem cells
Social Networks {👍}(6)
External Links {🔗}(93)
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