Here's how NATURE.COM makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

NATURE . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Nature.com Make Money
  6. How Much Does Nature.com Make
  7. Keywords
  8. Topics
  9. Questions
  10. Schema
  11. Social Networks
  12. External Links
  13. Analytics And Tracking
  14. Libraries
  15. Hosting Providers
  16. CDN Services

We are analyzing https://www.nature.com/articles/s41579-025-01163-0.

Title:
Microbiota in inflammatory bowel disease: mechanisms of disease and therapeutic opportunities | Nature Reviews Microbiology
Description:
Perturbations in the intestinal microbiome are strongly linked to the pathogenesis of inflammatory bowel disease (IBD). Bacteria, fungi and viruses all make up part of a complex multi-kingdom community colonizing the gastrointestinal tract, often referred to as the gut microbiome. They can exert various effects on the host that can contribute to an inflammatory state. Advances in screening, multiomics and experimental approaches have revealed insights into host–microbiota interactions in IBD and have identified numerous mechanisms through which the microbiota and its metabolites can exert a major influence on the gastrointestinal tract. Looking into the future, the microbiome and microbiota-associated processes will be likely to provide unparalleled opportunities for novel diagnostic, therapeutic and diet-inspired solutions for the management of IBD through harnessing rationally designed microbial communities, powerful bacterial and fungal metabolites, individually or in combination, to foster intestinal health. In this Review, we examine the current understanding of the cross-kingdom gut microbiome in IBD, focusing on bacterial and fungal components and metabolites. We examine therapeutic and diagnostic opportunities, the microbial metabolism, immunity, neuroimmunology and microbiome-inspired interventions to link mechanisms of disease and identify novel research and therapeutic opportunities for IBD. In this Review, Iliev, Ananthakrishnan and Guo explore the gut microbiota in inflammatory bowel disease, highlighting bacterial and fungal components, immune mechanisms, metabolites, links between the microbiota and enteric nervous system, as well as therapeutic and diagnostic opportunities.
Website Age:
30 years and 10 months (reg. 1994-08-11).

Matching Content Categories {📚}

  • Education
  • Science
  • Health & Fitness

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌆 Monumental Traffic: 20M - 50M visitors per month


Based on our best estimate, this website will receive around 42,194,993 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}


Display Ads {🎯}


The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.

Ads are managed by yourbow.com. Particular relationships are as follows:

Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.com

Reseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.com

How Much Does Nature.com Make? {💰}


Display Ads {🎯}

$531,700 per month
Our estimates place Nature.com's monthly online earnings from display ads at $354,480 to $974,820.

Keywords {🔍}

pubmed, article, scholar, google, cas, central, disease, gut, bowel, inflammatory, nature, microbiota, cell, intestinal, nat, microbiome, crohns, colitis, human, immunity, science, host, fungal, cells, rev, review, gastroenterol, ibd, microbial, patients, microbe, inflammation, ulcerative, transplantation, research, med, gastroenterology, acids, bile, access, iliev, bacteria, metabolites, diseases, sci, commensal, study, hepatol, immune, microbiol,

Topics {✒️}

privacy policy nature portfolio journals diet-inspired solutions advertising nature portfolio social media national library anti-fungal igg antibodies microbiota-mediated intracellular acidification ultra-processed food intake short-chain fatty acids iliev & chun-jun guo reprints inhibiting antibiotic-resistant enterobacteriaceae double-blind placebo-controlled trial gut-innervating nociceptors regulate microbiota-derived bile acids multi-omics integration analyses adherent-invasive escherichia coli data protection pandrug-resistant klebsiella pneumoniae fracture-related infection due gut microbiota-derived metabolites gene–microbiota interactions contribute intestinal neuro–immune axis plasmablast-skewed humoral response gov/ct2/show/nct05370885 publishing agreement bile-acid conjugations microbiome–host mammal line anti-integrin biologic therapy dectin-1-dependent lc3 recruitment personal data author information authors pre-adapted bacteriophage therapy springerlink instant access cross-kingdom gut microbiome human-derived isolates randomised placebo-controlled trial divergent innate immunomodulation permissions promote tissue protection il-23/il-17 immunity interleukin-23 restrains regulatory research corporation advanced research human intestinal bacteria promote intestinal inflammation card9-dependent induction microbiota-induced tnf

Questions {❓}

  • Gut mycobiota under scrutiny: fungal symbionts or environmental transients?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Microbiota in inflammatory bowel disease: mechanisms of disease and therapeutic opportunities
         description:Perturbations in the intestinal microbiome are strongly linked to the pathogenesis of inflammatory bowel disease (IBD). Bacteria, fungi and viruses all make up part of a complex multi-kingdom community colonizing the gastrointestinal tract, often referred to as the gut microbiome. They can exert various effects on the host that can contribute to an inflammatory state. Advances in screening, multiomics and experimental approaches have revealed insights into host–microbiota interactions in IBD and have identified numerous mechanisms through which the microbiota and its metabolites can exert a major influence on the gastrointestinal tract. Looking into the future, the microbiome and microbiota-associated processes will be likely to provide unparalleled opportunities for novel diagnostic, therapeutic and diet-inspired solutions for the management of IBD through harnessing rationally designed microbial communities, powerful bacterial and fungal metabolites, individually or in combination, to foster intestinal health. In this Review, we examine the current understanding of the cross-kingdom gut microbiome in IBD, focusing on bacterial and fungal components and metabolites. We examine therapeutic and diagnostic opportunities, the microbial metabolism, immunity, neuroimmunology and microbiome-inspired interventions to link mechanisms of disease and identify novel research and therapeutic opportunities for IBD. In this Review, Iliev, Ananthakrishnan and Guo explore the gut microbiota in inflammatory bowel disease, highlighting bacterial and fungal components, immune mechanisms, metabolites, links between the microbiota and enteric nervous system, as well as therapeutic and diagnostic opportunities.
         datePublished:2025-03-10T00:00:00Z
         dateModified:2025-03-24T00:00:00Z
         pageStart:1
         pageEnd:16
         sameAs:https://doi.org/10.1038/s41579-025-01163-0
         keywords:
            Bacteria
            Fungi
            Inflammation
            Inflammatory bowel disease
            Microbiome
            Life Sciences
            general
            Microbiology
            Medical Microbiology
            Parasitology
            Infectious Diseases
            Virology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41579-025-01163-0/MediaObjects/41579_2025_1163_Fig1_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41579-025-01163-0/MediaObjects/41579_2025_1163_Fig2_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41579-025-01163-0/MediaObjects/41579_2025_1163_Fig3_HTML.png
         isPartOf:
            name:Nature Reviews Microbiology
            issn:
               1740-1534
               1740-1526
            type:
               Periodical
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Iliyan D. Iliev
               url:http://orcid.org/0000-0003-0884-9749
               affiliation:
                     name:Weill Cornell Medicine
                     address:
                        name:Joan and Sanford I. Weill Department of Medicine, Gastroenterology and Hepatology Division, Weill Cornell Medicine, New York, USA
                        type:PostalAddress
                     type:Organization
                     name:Weill Cornell Medicine
                     address:
                        name:The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, New York, USA
                        type:PostalAddress
                     type:Organization
                     name:Weill Cornell Medicine
                     address:
                        name:Department of Microbiology and Immunology, Weill Cornell Medicine, New York, USA
                        type:PostalAddress
                     type:Organization
                     name:Cornell University
                     address:
                        name:Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, Cornell University, New York, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Ashwin N. Ananthakrishnan
               affiliation:
                     name:Massachusetts General Hospital and Harvard Medical School
                     address:
                        name:Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Chun-Jun Guo
               url:http://orcid.org/0000-0002-7227-4591
               affiliation:
                     name:Weill Cornell Medicine
                     address:
                        name:Joan and Sanford I. Weill Department of Medicine, Gastroenterology and Hepatology Division, Weill Cornell Medicine, New York, USA
                        type:PostalAddress
                     type:Organization
                     name:Weill Cornell Medicine
                     address:
                        name:The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, New York, USA
                        type:PostalAddress
                     type:Organization
                     name:Weill Cornell Medicine
                     address:
                        name:Department of Microbiology and Immunology, Weill Cornell Medicine, New York, USA
                        type:PostalAddress
                     type:Organization
                     name:Cornell University
                     address:
                        name:Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, Cornell University, New York, USA
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Microbiota in inflammatory bowel disease: mechanisms of disease and therapeutic opportunities
      description:Perturbations in the intestinal microbiome are strongly linked to the pathogenesis of inflammatory bowel disease (IBD). Bacteria, fungi and viruses all make up part of a complex multi-kingdom community colonizing the gastrointestinal tract, often referred to as the gut microbiome. They can exert various effects on the host that can contribute to an inflammatory state. Advances in screening, multiomics and experimental approaches have revealed insights into host–microbiota interactions in IBD and have identified numerous mechanisms through which the microbiota and its metabolites can exert a major influence on the gastrointestinal tract. Looking into the future, the microbiome and microbiota-associated processes will be likely to provide unparalleled opportunities for novel diagnostic, therapeutic and diet-inspired solutions for the management of IBD through harnessing rationally designed microbial communities, powerful bacterial and fungal metabolites, individually or in combination, to foster intestinal health. In this Review, we examine the current understanding of the cross-kingdom gut microbiome in IBD, focusing on bacterial and fungal components and metabolites. We examine therapeutic and diagnostic opportunities, the microbial metabolism, immunity, neuroimmunology and microbiome-inspired interventions to link mechanisms of disease and identify novel research and therapeutic opportunities for IBD. In this Review, Iliev, Ananthakrishnan and Guo explore the gut microbiota in inflammatory bowel disease, highlighting bacterial and fungal components, immune mechanisms, metabolites, links between the microbiota and enteric nervous system, as well as therapeutic and diagnostic opportunities.
      datePublished:2025-03-10T00:00:00Z
      dateModified:2025-03-24T00:00:00Z
      pageStart:1
      pageEnd:16
      sameAs:https://doi.org/10.1038/s41579-025-01163-0
      keywords:
         Bacteria
         Fungi
         Inflammation
         Inflammatory bowel disease
         Microbiome
         Life Sciences
         general
         Microbiology
         Medical Microbiology
         Parasitology
         Infectious Diseases
         Virology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41579-025-01163-0/MediaObjects/41579_2025_1163_Fig1_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41579-025-01163-0/MediaObjects/41579_2025_1163_Fig2_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41579-025-01163-0/MediaObjects/41579_2025_1163_Fig3_HTML.png
      isPartOf:
         name:Nature Reviews Microbiology
         issn:
            1740-1534
            1740-1526
         type:
            Periodical
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Iliyan D. Iliev
            url:http://orcid.org/0000-0003-0884-9749
            affiliation:
                  name:Weill Cornell Medicine
                  address:
                     name:Joan and Sanford I. Weill Department of Medicine, Gastroenterology and Hepatology Division, Weill Cornell Medicine, New York, USA
                     type:PostalAddress
                  type:Organization
                  name:Weill Cornell Medicine
                  address:
                     name:The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, New York, USA
                     type:PostalAddress
                  type:Organization
                  name:Weill Cornell Medicine
                  address:
                     name:Department of Microbiology and Immunology, Weill Cornell Medicine, New York, USA
                     type:PostalAddress
                  type:Organization
                  name:Cornell University
                  address:
                     name:Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, Cornell University, New York, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Ashwin N. Ananthakrishnan
            affiliation:
                  name:Massachusetts General Hospital and Harvard Medical School
                  address:
                     name:Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Chun-Jun Guo
            url:http://orcid.org/0000-0002-7227-4591
            affiliation:
                  name:Weill Cornell Medicine
                  address:
                     name:Joan and Sanford I. Weill Department of Medicine, Gastroenterology and Hepatology Division, Weill Cornell Medicine, New York, USA
                     type:PostalAddress
                  type:Organization
                  name:Weill Cornell Medicine
                  address:
                     name:The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, New York, USA
                     type:PostalAddress
                  type:Organization
                  name:Weill Cornell Medicine
                  address:
                     name:Department of Microbiology and Immunology, Weill Cornell Medicine, New York, USA
                     type:PostalAddress
                  type:Organization
                  name:Cornell University
                  address:
                     name:Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, Cornell University, New York, USA
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical"]:
      name:Nature Reviews Microbiology
      issn:
         1740-1534
         1740-1526
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Weill Cornell Medicine
      address:
         name:Joan and Sanford I. Weill Department of Medicine, Gastroenterology and Hepatology Division, Weill Cornell Medicine, New York, USA
         type:PostalAddress
      name:Weill Cornell Medicine
      address:
         name:The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, New York, USA
         type:PostalAddress
      name:Weill Cornell Medicine
      address:
         name:Department of Microbiology and Immunology, Weill Cornell Medicine, New York, USA
         type:PostalAddress
      name:Cornell University
      address:
         name:Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, Cornell University, New York, USA
         type:PostalAddress
      name:Massachusetts General Hospital and Harvard Medical School
      address:
         name:Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
         type:PostalAddress
      name:Weill Cornell Medicine
      address:
         name:Joan and Sanford I. Weill Department of Medicine, Gastroenterology and Hepatology Division, Weill Cornell Medicine, New York, USA
         type:PostalAddress
      name:Weill Cornell Medicine
      address:
         name:The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, New York, USA
         type:PostalAddress
      name:Weill Cornell Medicine
      address:
         name:Department of Microbiology and Immunology, Weill Cornell Medicine, New York, USA
         type:PostalAddress
      name:Cornell University
      address:
         name:Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, Cornell University, New York, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Iliyan D. Iliev
      url:http://orcid.org/0000-0003-0884-9749
      affiliation:
            name:Weill Cornell Medicine
            address:
               name:Joan and Sanford I. Weill Department of Medicine, Gastroenterology and Hepatology Division, Weill Cornell Medicine, New York, USA
               type:PostalAddress
            type:Organization
            name:Weill Cornell Medicine
            address:
               name:The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, New York, USA
               type:PostalAddress
            type:Organization
            name:Weill Cornell Medicine
            address:
               name:Department of Microbiology and Immunology, Weill Cornell Medicine, New York, USA
               type:PostalAddress
            type:Organization
            name:Cornell University
            address:
               name:Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, Cornell University, New York, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Ashwin N. Ananthakrishnan
      affiliation:
            name:Massachusetts General Hospital and Harvard Medical School
            address:
               name:Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Chun-Jun Guo
      url:http://orcid.org/0000-0002-7227-4591
      affiliation:
            name:Weill Cornell Medicine
            address:
               name:Joan and Sanford I. Weill Department of Medicine, Gastroenterology and Hepatology Division, Weill Cornell Medicine, New York, USA
               type:PostalAddress
            type:Organization
            name:Weill Cornell Medicine
            address:
               name:The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, New York, USA
               type:PostalAddress
            type:Organization
            name:Weill Cornell Medicine
            address:
               name:Department of Microbiology and Immunology, Weill Cornell Medicine, New York, USA
               type:PostalAddress
            type:Organization
            name:Cornell University
            address:
               name:Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, Cornell University, New York, USA
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Joan and Sanford I. Weill Department of Medicine, Gastroenterology and Hepatology Division, Weill Cornell Medicine, New York, USA
      name:The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, New York, USA
      name:Department of Microbiology and Immunology, Weill Cornell Medicine, New York, USA
      name:Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, Cornell University, New York, USA
      name:Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
      name:Joan and Sanford I. Weill Department of Medicine, Gastroenterology and Hepatology Division, Weill Cornell Medicine, New York, USA
      name:The Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, New York, USA
      name:Department of Microbiology and Immunology, Weill Cornell Medicine, New York, USA
      name:Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, Cornell University, New York, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(1)

External Links {🔗}(767)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Prism.js
  • Zoom.js

Emails and Hosting {✉️}

Mail Servers:

  • mxa-002c5801.gslb.pphosted.com
  • mxb-002c5801.gslb.pphosted.com

Name Servers:

  • pdns1.ultradns.net
  • pdns2.ultradns.net
  • pdns3.ultradns.org
  • pdns4.ultradns.org
  • pdns5.ultradns.info
  • pdns6.ultradns.co.uk

CDN Services {📦}

  • Crossref

5.47s.