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Title[redir]:
Ruminococcus gnavus, a member of the human gut microbiome associated with Crohn’s disease, produces an inflammatory polysaccharide - PMC
Description:
The bacteria that live within the human gut play crucial roles in regulating our primary metabolism, protecting us from pathogens, and developing our immune system. Imbalances in bacterial community structure have been implicated in many diseases, ...
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Keywords {🔍}
gnavus, glucorhamnan, polysaccharide, inflammatory, disease, gut, google, scholar, doi, rhamnose, pubmed, gene, glucose, cluster, rumgna, pmc, article, linked, fig, ppm, genes, polysaccharides, appendix, unit, tlr, free, immune, tnfα, backbone, analysis, supplementary, human, crohns, bowel, cells, repeating, biosynthetic, medium, mbmdcs, purified, bacteria, cell, data, media, monosaccharide, nmr, patients, microbiota, acid, culture,
Topics {✒️}
org/lookup/suppl/doi tangential flow-filtration apparatus n-acetyl–muramic acid β-d-glucuronic acid lytr/cpsa/psr brain-heart infusion broths pmc beta search confounding media-derived materials analytical size-exclusion chromatography gas chromatography–mass spectrometry bacto brain-heart infusion real-time pcr carried 1h-31p hmbc correlations size-exclusion filters showed tlr4-knockout mice failed cell-wall rhamnose-glucose polysaccharides 10-kda molecular-weight cutoff tnfα-inducing polysaccharide produced bacto todd-hewitt broth dose-dependent manner roughly supplementary materials included bacteria-free zone cell-free media brain-heart infusion enzyme-linked immunosorbent assay full nmr spectra tlr2-knockout mice [toll cell-free supernatant [google scholar] 18 [google scholar] 24 size-exclusion chromatography canonical teichoic acid publisher site pdf supplementary file pnas human inflammatory responses tnfα-inducing factor contaminating teichoic acid full-length glucorhamnan noesy showed cross-peaks ibd mucosa augment classical lancefield antigen hsqc-tocsy showed h1 dose-dependent fashion license information pmcid supporting information online biosynthetic gene cluster potential gene cluster intestinal mucosal surface hsqc spectrum zoom wild-type strain
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