
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity - PMC
Description:
B cells, which are critical for intestinal homeostasis, remain understudied in ulcerative colitis (UC). In this study, we recruited three cohorts of patients with UC (primary cohort, n = 145; validation cohort 1, n = 664; and validation cohort 2, n ...
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Keywords {🔍}
cells, patients, data, cell, fig, igg, pubmed, google, scholar, doi, hcs, expression, disease, supplementary, genes, pcs, colonic, iga, pbs, pmc, article, gene, extended, free, inflamed, cluster, clusters, test, naive, intestinal, active, table, total, human, colon, samples, clones, circulating, mannwhitney, analysis, frequency, increased, signature, biopsies, twotailed, blood, rna, tph, singlecell, box,
Topics {✒️}
cd19+cd38−cd10−cd27+igm−igd− switched memory cd45+cd19+cd38−cd10−igd+igm+ cd45+cd19+cd38−cd10−igd−igm− β7-integrin+cd19+/−cd38++cd27+igd sm cd19+cd38−cd27+igm−igd− naive cd19+cd38−cd10−igm+igd+ cd19+cd38++cd10−cd27+igd− igg+iga−igm−cd38++cd27+ colonic pc cd19+cd38−cd10−igm+igd+ cd19+cd38−cd10−igm−igd− heat-map showing color-coded cd19+/intcd38++cd27+igd− pbs live cd45+cd38++cd27+cd19+ cd19+/intcd38++cd27+igd− cells supplementary tables nihms1802699-supplement-supplementary_tables universidades grants rti2018-093894-b-i00 g-protein-coupled receptor gpr171 live cd45+cd3+cd4+cd45ra− cells cd27+cd38++cd19+cd45+ cd27+cd38++cd19−cd45+ cd27+cd38++cd19−cd45− pre-ranked rna-seq dataset cd19+/intcd38hicd27+igd−β7+ recent scrna-seq-based studies37 single-end rna-seq reads heatmap showing color-coded mouse anti-human αvβ6 malaria-induced interferon-γ drives β7+ gut-homing pbs/pcs circulating β7-integrin-expressing pbs runs strikingly anti-parallel sided mann–whitney u-test mucin-mediated biofilm formation single-cell rna-seq data circulating gut-homing pbs/pcs pd-1hi cd4+cd45ra− cells chronic antigen-mediated overstimulation ek’balam algorithm based wilcoxon rank-sum test pre-mixed lyophilized antibody k-nearest neighbor graphs radio-sterilized pvdf membrane ifnα-driven lupus nephritis anti-integrin αvβ6 autoantibody pmc beta search gut-homing integrin β7 pd-1hitigit+icos+cd45ra− heat-induced epitope retrieval multi-parametric flow cytometry k-nn graph partitions
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