
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Combination of pre-adapted bacteriophage therapy and antibiotics for treatment of fracture-related infection due to pandrug-resistant Klebsiella pneumoniae - PMC
Description:
A 30-year-old bombing victim with a fracture-related pandrug-resistant Klebsiella pneumoniae infection after long-term (>700 days) antibiotic therapy is treated with a pre-adapted bacteriophage along with meropenem and colistin, followed by ...
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Keywords {🔍}
phage, doi, data, pneumoniae, fig, pubmed, google, scholar, therapy, phages, pmc, article, bacterial, isolates, free, supplementary, treatment, antibiotic, infection, patients, antibiotics, isolate, preadapted, klebsiella, biofilms, days, day, activity, genome, ceftazidimeavibactam, clinical, source, database, patient, bacteria, resistance, strain, genes, min, ncbi, combination, information, open, determined, sequencing, analysis, illumina, due, fri, combinations,
Topics {✒️}
carbapenem-hydrolyzing β-lactamase oxa-4815 treat orthopedic-device-related infections6 kirby-bauer disk-diffusion method author contributions fda-approved labeling information extended-spectrum β-lactamases diagnosing fracture-related infection orthopaedic-device-related infections carbapenem-resistant enterobacteriaceae advocates accession codes srr13350373-srr13350378 accession codes cp066511-cp066515 competing interests post-traumatic deafness due fracture-related infection due carbon-coated copper grids phage-neutralizing antibodies hampered pmc beta search combat antibiotic-resistant bacteria oxa-48-producing klebsiella pneumoniae license information pmcid long-term antibiotic therapy successive computed-tomography scanners combined phage-antibiotic therapy mid-logarithmic phase bacteria single-step growth curve pre-adapting parasitic phages methods ethical approval footnotes publisher combined phage-antibiotic treatment data availability statements data availability statement pre-adapted bacteriophage therapy disk diffusion method pre-adapted phage m1 fracture-related infection peer review ceftazidime/avibactam finally led low success rates supplementary information peer reviewer reports topical phage therapy phage-antibiotic combination treatment mueller hinton agar diabetic foot infections supplementary data files tetrazolium dye due sequence read archive adaptive immune system pandrug-resistant bacteria synthesize neutralizing antibodies
Questions {❓}
- Bacteriophage therapy as a treatment strategy for orthopaedic-device-related infections: where do we stand?
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