NCBI . NLM . NIH . GOV {
}
We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC4671824/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC4671824/. The analysis below is for the second page.
Title[redir]:
Single-cell Genomics Unveils Critical Regulators of Th17 cell Pathogenicity - PMC
Description:
Extensive cellular heterogeneity exists within specific immune-cell subtypes classified as a single lineage, but its molecular underpinnings are rarely characterized at a genomic scale. Here, we use single-cell RNA-seq to investigate the molecular ...
Title[redir]:
Single-cell Genomics Unveils Critical Regulators of Th17 cell Pathogenicity - PMC
Description:
Extensive cellular heterogeneity exists within specific immune-cell subtypes classified as a single lineage, but its molecular underpinnings are rarely characterized at a genomic scale. Here, we use single-cell RNA-seq to investigate the molecular ...
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🌠 Phenomenal Traffic: 5M - 10M visitors per month
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Keywords {🔍}
cells, figure, doi, genes, pubmed, google, scholar, cell, pmc, article, experimental, free, expression, nature, vitro, procedures, vivo, table, signature, pathogenic, gpr, supplemental, toso, ila, regulatory, memory, singlecell, differentiation, states, pathogenicity, cns, mice, rnaseq, eae, plzp, pdf, disease, proinflammatory, differentiated, gene, key, nihmssupplementpdf, effector, analysis, tgfβil, correlation, signatures, test, nihmssupplementxlsx, xlsx,
Topics {✒️}
harvested cd3+cd4+il-17a/gfp+ cells genome-wide meta-analysis increases conventional pathogen-free facility full-length mrna-seq results rna-seq profiling il-17a/gfp+ sorted cells pro-inflammatory cytokine il-17a pmc beta search dotted/solid line corresponds tgf-β1+il-6 differentiation condition single-cell rna-seq cell-mediated immune mechanisms il-17a/gfp+ spanning cell-mediated intestinal inflammation hampered il-17a production nod/scid recipient mice il-17a–gfp+ mice pro-survival gene lacking il-1β+il-6+il-23 seventeen-colour flow cytometry mog35–55-specific il-17a single-cell heterogeneity shows reduced il-17a production single-cell expression levels low cell-cycle activity il-23r−/− cells differentiated tgf-β1+il-6 condition dampens t-cell activation transposon-based library construction tgf-β1+il-6 differentiation gut-derived th17 cells disease-specific molecular events previous population-level approaches references antebi ye il-17a+ cells compared pro-inflammatory th17 cytokines supplementary materials included il-17a-based sorting c-rel transcription factor il-17a/gfp+ progressive th17-cell states single-cell expression distribution t-cell pathogenicity regulators t-cell receptor diversity immune system strikes rna-seq profiles gpr65−/− t-cells differentiated fas-induced apoptosis t-cell activation genes single-cell levels
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