PMC . NCBI . NLM . NIH . GOV {
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We are analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC3183752/.
Title:
Activation of the mitochondrial permeability transition pore modulates Ca2+ responses to physiological stimuli in adult neurons - PMC
Description:
The participation of mitochondria in cellular and neuronal Ca2+ homeostatic networks is now well accepted. Yet, critical tests of specific mitochondrial pathways in neuronal Ca2+ responses have been hampered because the identity of mitochondrial ...
Website Age:
27 years and 8 months (reg. 1997-10-02).
Title:
Activation of the mitochondrial permeability transition pore modulates Ca2+ responses to physiological stimuli in adult neurons - PMC
Description:
The participation of mitochondria in cellular and neuronal Ca2+ homeostatic networks is now well accepted. Yet, critical tests of specific mitochondrial pathways in neuronal Ca2+ responses have been hampered because the identity of mitochondrial ...
Website Age:
27 years and 8 months (reg. 1997-10-02).
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- Education
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Custom-built
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Traffic Estimate {📈}
What is the average monthly size of pmc.ncbi.nlm.nih.gov audience?
🌠 Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,006,616 visitors per month in the current month.
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Keywords {🔍}
mitochondrial, neurons, doi, cypdko, mitochondria, ptp, cytosolic, pubmed, google, scholar, levels, responses, fig, neuronal, cell, atp, stimulation, kcl, adult, activation, response, opening, mitorp, min, bernardi, death, reported, pmc, calcium, cypd, cells, membrane, csa, article, permeability, transition, free, simultaneous, results, cortical, role, cellular, dynamics, imaging, ionomycin, higher, pore, viability, potential, perfusion,
Topics {✒️}
peripheral benzodiazepine receptor sr/er-mitochondrial local communication 5-trisphosphate-dependent ca2+ signals high-resolution time-lapse imaging ca2+-free buffer immediately wild-type mice pmc beta search high-speed wavelength switcher mitochondrial love-hate triangle inositol trisphosphate gfp-based ca2+ sensors green fluorescent protein calcium-permeable ampa channels permeability transition pore ppif-null mouse colonies wild-type glutamate-induced calcium deregulation bonferroni post-hoc test stimulus-evoked calcium signals hypoxic-ischemic brain injury receptor-generated ip3 cypd-ko neurons reflect cypd-ko cortical neurons mitochondrial permeability transition cypd-dependent neuroprotection tested cypd-ko neurons supports fluorescent probe targeted supplementary material fig cypd-ko neurons treated cypd-ko adult neurons higher ca2+ set-point endoplasmic reticulum references abramov ay poly-d-lysine cypd-dependent ptp activation ratiometric indicator furaff supporting information supplied mitochondrially targeted yfp intact cypd-ko neurons cypd-ko neurons compared high-conductance channel enhanced ca2+ capacity mitochondrial ca2+ uptake transduction mechanism based enhancing ca2+ uptake fluorescent dye tmrm myelin basic protein accumulate higher levels adult cortical neurons sustaining signals arising
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External Links {🔗}(211)
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