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  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Doi.org Make Money
  6. Keywords
  7. Topics
  8. Schema
  9. Social Networks
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We began analyzing https://www.nature.com/articles/s41591-018-0014-x, but it redirected us to https://www.nature.com/articles/s41591-018-0014-x. The analysis below is for the second page.

Title[redir]:
Understanding the tumor immune microenvironment (TIME) for effective therapy | Nature Medicine
Description:
The clinical successes in immunotherapy have been both astounding and at the same time unsatisfactory. Countless patients with varied tumor types have seen pronounced clinical response with immunotherapeutic intervention; however, many more patients have experienced minimal or no clinical benefit when provided the same treatment. As technology has advanced, so has the understanding of the complexity and diversity of the immune context of the tumor microenvironment and its influence on response to therapy. It has been possible to identify different subclasses of immune environment that have an influence on tumor initiation and response and therapy; by parsing the unique classes and subclasses of tumor immune microenvironment (TIME) that exist within a patient’s tumor, the ability to predict and guide immunotherapeutic responsiveness will improve, and new therapeutic targets will be revealed. The tumor immune microenvironment influences tumor progression and response to immunotherapy; its further characterization will improve therapeutic outcome.

Matching Content Categories {📚}

  • Education
  • Health & Fitness
  • Science

Content Management System {📝}

What CMS is doi.org built with?

Custom-built

No common CMS systems were detected on Doi.org, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of doi.org audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


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How Does Doi.org Make Money? {💸}

We can't tell how the site generates income.

The purpose of some websites isn't monetary gain; they're meant to inform, educate, or foster collaboration. Everyone has unique reasons for building websites. This could be an example. Doi.org could be secretly minting cash, but we can't detect the process.

Keywords {🔍}

pubmed, article, google, scholar, cas, central, cancer, cell, nature, tumor, immune, immunity, cells, usa, nat, immunol, macrophages, metastasis, immunotherapy, access, med, pancreatic, microenvironment, promotes, science, lung, breast, content, dendritic, medicine, therapy, colorectal, rev, department, university, cookies, patients, clin, exp, mice, tumors, inflammation, progression, molecular, responses, neutrophils, privacy, time, robert, response,

Topics {✒️}

permissions reprints nature portfolio journals biomedical research privacy policy nature portfolio myeloid-derived suppressor cells facilitates anti-pd-l1 efficacy anti-pd-l1 antibody mpdl3280a crispr/cas-mediated genome engineering gene-expression-based retrospective study advertising t-cell-inflamed tumor microenvironment social media cyclooxygenase-dependent tumor growth open-label development facilitate breast-tumour metastasis triple-negative breast cancer biomimetic gold nano-modulator cell-mediated tumor cytotoxicity batf3 deficiency reveals suppress anti-tumor immunity suzanne ostrand-rosenberg cell-autonomous tumor suppression cancer-promoting siglecfhigh neutrophils braf-mapk signaling pathway single-cell rna-seq inducing pmn-mdsc infiltration crispr/cas systems personal data angiotensin ii drives tumor antigen trafficking inducing t-cell tolerance paired single-cell analyses nature+ nature 515 nature 523 nature 475 nature 437 nature 545 nature 539 nature 531 nature 528 nature 522 nature 507 nature early lung adenocarcinoma multiplex genome engineering tumor-induced tolerance data protection

Schema {🗺️}

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         description:The clinical successes in immunotherapy have been both astounding and at the same time unsatisfactory. Countless patients with varied tumor types have seen pronounced clinical response with immunotherapeutic intervention; however, many more patients have experienced minimal or no clinical benefit when provided the same treatment. As technology has advanced, so has the understanding of the complexity and diversity of the immune context of the tumor microenvironment and its influence on response to therapy. It has been possible to identify different subclasses of immune environment that have an influence on tumor initiation and response and therapy; by parsing the unique classes and subclasses of tumor immune microenvironment (TIME) that exist within a patient’s tumor, the ability to predict and guide immunotherapeutic responsiveness will improve, and new therapeutic targets will be revealed. The tumor immune microenvironment influences tumor progression and response to immunotherapy; its further characterization will improve therapeutic outcome.
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               type:PostalAddress
            type:Organization
      name:Dmitry I. Gabrilovich
      affiliation:
            name:The Wistar Institute
            address:
               name:The Wistar Institute, Philadelphia, USA
               type:PostalAddress
            type:Organization
      name:Suzanne Ostrand-Rosenberg
      url:http://orcid.org/0000-0002-2095-9732
      affiliation:
            name:University of Maryland Baltimore County
            address:
               name:Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, USA
               type:PostalAddress
            type:Organization
            name:University of Utah
            address:
               name:Huntsman Cancer Institute and Department of Pathology, University of Utah, Salt Lake City, USA
               type:PostalAddress
            type:Organization
      name:Catherine C. Hedrick
      affiliation:
            name:La Jolla Institute for Allergy and Immunology
            address:
               name:Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, USA
               type:PostalAddress
            type:Organization
      name:Robert H. Vonderheide
      affiliation:
            name:University of Pennsylvania
            address:
               name:Department of Medicine, Abramson Cancer Center, University of Pennsylvania, Philadelphia, USA
               type:PostalAddress
            type:Organization
      name:Mikael J. Pittet
      affiliation:
            name:Massachusetts General Hospital
            address:
               name:Center for Systems Biology, Massachusetts General Hospital, Boston, USA
               type:PostalAddress
            type:Organization
      name:Rakesh K. Jain
      affiliation:
            name:Massachusetts General Hospital and Harvard Medical School
            address:
               name:Edwin L. Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
               type:PostalAddress
            type:Organization
      name:Weiping Zou
      affiliation:
            name:University of Michigan School of Medicine
            address:
               name:Department of Surgery, University of Michigan School of Medicine, Ann Arbor, USA
               type:PostalAddress
            type:Organization
      name:T. Kevin Howcroft
      affiliation:
            name:NCI, NIH
            address:
               name:Division of Cancer Biology, NCI, NIH, Bethesda, USA
               type:PostalAddress
            type:Organization
      name:Elisa C. Woodhouse
      affiliation:
            name:NCI, NIH
            address:
               name:Division of Cancer Biology, NCI, NIH, Bethesda, USA
               type:PostalAddress
            type:Organization
      name:Robert A. Weinberg
      affiliation:
            name:Whitehead Institute for Biomedical Research
            address:
               name:Whitehead Institute for Biomedical Research, Cambridge, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Matthew F. Krummel
      url:http://orcid.org/0000-0001-7915-3533
      affiliation:
            name:University of California, San Francisco
            address:
               name:Department of Pathology, University of California, San Francisco, San Francisco, USA
               type:PostalAddress
            type:Organization
            name:University of California, San Francisco
            address:
               name:UCSF Immunoprofiler Initiative, University of California, San Francisco, San Francisco, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Pathology, University of California, San Francisco, San Francisco, USA
      name:Department of Pathology, University of California, San Francisco, San Francisco, USA
      name:Department of Pathology, University of California, San Francisco, San Francisco, USA
      name:UCSF Immunoprofiler Initiative, University of California, San Francisco, San Francisco, USA
      name:Cold Spring Harbor Laboratory, Cold Spring Harbor, USA
      name:Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, USA
      name:Department of Cell, Developmental & Cancer Biology, Oregon Health and Science University, Portland, USA
      name:The Wistar Institute, Philadelphia, USA
      name:Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, USA
      name:Huntsman Cancer Institute and Department of Pathology, University of Utah, Salt Lake City, USA
      name:Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, USA
      name:Department of Medicine, Abramson Cancer Center, University of Pennsylvania, Philadelphia, USA
      name:Center for Systems Biology, Massachusetts General Hospital, Boston, USA
      name:Edwin L. Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
      name:Department of Surgery, University of Michigan School of Medicine, Ann Arbor, USA
      name:Division of Cancer Biology, NCI, NIH, Bethesda, USA
      name:Division of Cancer Biology, NCI, NIH, Bethesda, USA
      name:Whitehead Institute for Biomedical Research, Cambridge, USA
      name:Department of Pathology, University of California, San Francisco, San Francisco, USA
      name:UCSF Immunoprofiler Initiative, University of California, San Francisco, San Francisco, USA
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