
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses - PMC
Description:
To guide the design of immunotherapy strategies for patients with early stage lung tumors, we developed a multiscale immune profiling strategy to map the immune landscape of early lung adenocarcinoma lesions to search for tumor-driven immune ...
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Keywords {π}
tumor, cells, cell, lung, expression, doi, cat, antihuman, clone, patients, figure, nlung, tissue, immune, plots, bar, normalized, google, scholar, macrophages, adenocarcinoma, fluidigm, pubmed, showing, patient, analysis, single, rrid, data, figures, lesions, tumors, pmc, stage, biolegend, cancer, metaclusters, paired, clusters, frequency, article, tissues, blood, representative, expressed, levels, free, site, tls, compared,
Topics {βοΈ}
ΞΌm-thick formalin-fixed paraffin-embedded peroxisome proliferator-activated receptor-gamma leaving dna+cd45+cisplatinlow events org/web/packages/ggplot2/index anti-pd-l1 antibody mpdl3280a mars-seq single-cell sorting pmc beta search single-cell rna sequencing post-sort confirmation gatings kaplan-meir curves showing single- cell rna-seq single cell rna-seq t-cell receptor profiling [google scholar] desch [google scholar] wendel glycerol-based mounting medium performing paired t-tests cross-single-cell contamination visualize high-dimensional data marker-free decomposition bias-controlled multiplex pcr anti-human hla class anti-human pd-l1 anti-human dc-lamp membrane-bound protein important reduced t-effector/treg ratio anti-pd-1 mab blockade produce rna-seq libraries facilitate breast-tumour metastasis intra-tumoral cd141+ dc van der maaten rank-based correlation coefficient references aberle dr lung-draining lymph nodes small-cell lung cancer pd-l1hicd64hicd14hipparΞ³hiil-6hi macrophages distinguish tumor-driven immune metastatic pd-l1-selected potent anti-tumor immunity data-driven phenotypic dissection reduced lung-cancer mortality normalized pd-l1 expression dieu-nosjean mc cell targeting immunotherapies normal tissue-imprinting cues tumor-produced soluble molecules supplementary material 1 batf3 deficiency reveals anti-pd-1 checkpoint blockade //cranr-projectorg/package=rtsne
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