
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Age-dependent dysregulation of innate immunity - PMC
Description:
As we age, the innate immune system becomes dysregulated and is characterized by persistent inflammatory responses that involve multiple immune and non-immune cell types, and that vary depending on the cell activation state and tissue context. This ...
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Keywords {🔍}
doi, google, scholar, pubmed, pmc, article, cells, cell, free, tlr, mice, aged, production, immune, expression, ageing, aging, ageassociated, immunol, innate, human, older, responses, impaired, function, infection, increased, inflammation, cytokine, inflammatory, adults, dcs, humans, activation, signalling, response, young, studies, decreased, individuals, age, neutrophil, proinflammatory, disease, vaccine, mouse, macrophages, protein, neutrophils, dendritic,
Topics {✒️}
granulocyte-macrophage colony-stimulating factor lineage−mhc class ii+cd11c+ tram—trif-related adaptor molecule specific cd4+-t-cell priming nuclear factor-kappab-dependent reversal trif—toll/il1 receptor domain nf-κb-dependent inflammatory state cell surface-bound il-1alpha tlr1/tlr2-induced cytokine production dc-sign-dependent interaction bone marrow-derived dcs pmc beta search mhc-ii antigen presentation tlr4-mediated pro-inflammatory responses regulatory t-cell responses circulating cell-free dna tlr-induced cytokine production97 human monocyte-derived dcs36 ssrna-induced cytokine production36 c-reactive protein levels myeloid-derived suppressor cells adapter-inducing interferon-β double-stranded dna breaks nf-κb-dependent pathways enhances t-cell responses tlr-induced cytokine production37 resultant pro-inflammatory state nzb/nzw f1 mice beta-estradiol inhibits expression impaired antigen-induced cd8+ hematopoietic stem cells synthetic ligand-mediated function low-grade systemic inflammation pro-inflammatory activated state tlr-induced cytokine production elevated pro-inflammatory state monocyte-related chemokine pathways adipose tissue-specific knockout stem cell compartment influenza virus-induced type unique klrg1-negative subset tlr2-dependent cytokine production {beta}-stimulated microglial activation decreased pi-3-kinase activation il-23p19 gene expression tlr-dependent cytokine production cd4+cd11b+ cdc subsets tlr8-dependent cytokine production methicillin-resistant staphylococcus aureus heightened pro-inflammatory environment
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- Should the human microbiome be considered when developing vaccines?
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- How much income is https://www.nlm.nih.gov/accessibility.html earning monthly?
- How much income does https://www.nlm.nih.gov/careers/careers.html have?
- How much does https://www.nlm.nih.gov/ make?
- How much does https://www.nih.gov/ generate monthly?
- How much profit does https://www.hhs.gov/ make?
- https://www.usa.gov/'s total income per month
Analytics and Tracking {📊}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {📚}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi