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NATURE . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Nature.com Make Money
  6. How Much Does Nature.com Make
  7. Keywords
  8. Topics
  9. Questions
  10. Schema
  11. Social Networks
  12. External Links
  13. Analytics And Tracking
  14. Libraries
  15. Hosting Providers
  16. CDN Services

We are analyzing https://www.nature.com/articles/s41568-020-00320-2.

Title:
The metabolism of cancer cells during metastasis | Nature Reviews Cancer
Description:
Metastasis formation is the major cause of death in most patients with cancer. Despite extensive research, targeting metastatic seeding and colonization is still an unresolved challenge. Only recently, attention has been drawn to the fact that metastasizing cancer cells selectively and dynamically adapt their metabolism at every step during the metastatic cascade. Moreover, many metastases display different metabolic traits compared with the tumours from which they originate, enabling survival and growth in the new environment. Consequently, the stage-dependent metabolic traits may provide therapeutic windows for preventing or reducing metastasis, and targeting the new metabolic traits arising in established metastases may allow their eradication. This Review describes the metabolic rewiring that occurs in cancer cells transitioning through the metastatic cascade and discusses the evidence for metabolically distinct features of primary tumours and metastases.
Website Age:
30 years and 10 months (reg. 1994-08-11).

Matching Content Categories {📚}

  • Education
  • Health & Fitness
  • Science

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌆 Monumental Traffic: 20M - 50M visitors per month


Based on our best estimate, this website will receive around 41,362,249 visitors per month in the current month.

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How Does Nature.com Make Money? {💸}


Display Ads {🎯}


The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.

Ads are managed by yourbow.com. Particular relationships are as follows:

Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.com

Reseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.com

How Much Does Nature.com Make? {💰}


Display Ads {🎯}

$521,200 per month
Our analysis indicates Nature.com generates between $347,485 and $955,583 monthly online from display ads.

Keywords {🔍}

pubmed, google, scholar, cancer, cas, central, metastasis, cell, cells, metabolic, breast, promotes, nature, tumor, metastatic, metabolism, acid, res, fatty, growth, nat, article, progression, lung, carcinoma, expression, human, melanoma, lipid, colorectal, pyruvate, fendt, metastases, mol, sci, biol, survival, med, formation, targeting, access, oncogene, metab, pathway, tumour, molecular, stem, signaling, potential, inhibition,

Topics {✒️}

permissions reprints cd36/stat3/nf-κb signaling axis akt/gsk-3β/β-catenin pathway nature portfolio journals privacy policy author information authors nature portfolio current scientific literature body mass index european research council fwo research projects ros–akt–nf-κb pathway hypoxia-inducible transcription factor-1α advertising tumour development fatty acid β-oxidation extensive research social media wnt/β-catenin pathway hinders mtorc1-dependent tumorigenesis hydrogen sulfide-targeted receptor caveolin-1/β-catenin pathway regulation src/erk pathway triple-negative breast cancer fatty acid oxidation glucose fatty-acid cycle single-cell rna-seq ldha-mediated warburg effect fatty acid synthesis stearoyl-coa desaturase 1 adipocyte-induced fabp4 expression fatty acid transport adipocyte-rich metastatic niche carnitine palmitoyl transferase-1a stage-dependent metabolic traits lkb1-deficient lung cancer organ-specific metastases obtained obesity-responsive murine model organ-specific cancer metabolism tissue-specific decellularized scaffolds fabp5/sp1/uca1 pathway small-cell lung cancer single-cell rna sequencing targeting metastasis-initiating cells age-dependent metabolic change facilitating epithelial–mesenchymal transition multiple omics data sarah-maria fendt fatty acid saturation inducing epithelial–mesenchymal transition

Questions {❓}

  • Lipid desaturation — the next step in targeting lipogenesis in cancer?
  • The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells?

Schema {🗺️}

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         description:Metastasis formation is the major cause of death in most patients with cancer. Despite extensive research, targeting metastatic seeding and colonization is still an unresolved challenge. Only recently, attention has been drawn to the fact that metastasizing cancer cells selectively and dynamically adapt their metabolism at every step during the metastatic cascade. Moreover, many metastases display different metabolic traits compared with the tumours from which they originate, enabling survival and growth in the new environment. Consequently, the stage-dependent metabolic traits may provide therapeutic windows for preventing or reducing metastasis, and targeting the new metabolic traits arising in established metastases may allow their eradication. This Review describes the metabolic rewiring that occurs in cancer cells transitioning through the metastatic cascade and discusses the evidence for metabolically distinct features of primary tumours and metastases.
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      headline:The metabolism of cancer cells during metastasis
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Social Networks {👍}(2)

External Links {🔗}(547)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Prism.js
  • Zoom.js

Emails and Hosting {✉️}

Mail Servers:

  • mxa-002c5801.gslb.pphosted.com
  • mxb-002c5801.gslb.pphosted.com

Name Servers:

  • pdns1.ultradns.net
  • pdns2.ultradns.net
  • pdns3.ultradns.org
  • pdns4.ultradns.org
  • pdns5.ultradns.info
  • pdns6.ultradns.co.uk

CDN Services {📦}

  • Crossref

4.54s.