NCBI . NLM . NIH . GOV {
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We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC5763507/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC5763507/. The analysis below is for the second page.
Title[redir]:
Inhibition of pyruvate carboxylase by 1α,25-dihydroxyvitamin D promotes oxidative stress in early breast cancer progression - PMC
Description:
Maintaining reductive-oxidative (redox) balance is an essential feature in breast cancer cell survival, with cellular metabolism playing an integral role in maintaining redox balance through its supply of reduced NADPH. In the present studies, the ...
Title[redir]:
Inhibition of pyruvate carboxylase by 1α,25-dihydroxyvitamin D promotes oxidative stress in early breast cancer progression - PMC
Description:
Maintaining reductive-oxidative (redox) balance is an essential feature in breast cancer cell survival, with cellular metabolism playing an integral role in maintaining redox balance through its supply of reduced NADPH. In the present studies, the ...
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Keywords {🔍}
cells, ohd, cancer, doi, breast, vehicle, treatment, mcfaras, fig, effect, cell, treated, epithelial, expression, pubmed, google, scholar, oxidative, measured, promoter, stress, pyruvate, pmc, redox, metabolism, nadph, ros, free, article, mrna, oaa, relative, balance, results, ppp, analysis, glucose, expressed, levels, studies, protein, decreased, assay, reduced, gshgssg, generation, gsh, flux, human, vdre,
Topics {✒️}
promoterless pgl3-basic-luc plasmid pgl3-basic-luc plasmid mcf10a-ras epithelial cells 2d-treated mcf10a-ras cells liquid chromatography-mass spectrometry mcf10a-erbb2 epithelial cells sensitizing mcf10a-ras cells challenging mcf10a-ras cells doxorubicin-induced oxidative damage promega gsh/gssg-glo™ assay pmc beta search mcf10a harvey-ras mcf10a-ras cells resulted mcf10a-ras cells independent pgl3-basic-luc vehicle mcf10a-ras cells treated glutathione reductase-mediated recycling glucose-stimulated insulin secretion mcf10a-erbb2 cells treated 2d-mediated pro-oxidative effect real-time quantitative pcr nadp/nadph-glo assay intracellular ribose-5-phosphate concentration gov/statfacts/html/breast glutathione disulfide/glutathione couple transformed epithelial cells gsh/gssg ratio measurements stable transfected cells prostate epithelial cells dcfh-da stock solution shrna lentiviral plasmids real time-pcr analysis mcf10a-ras cells human pc gene breast epithelial cells kras-regulated metabolic pathway methods mol biol renilla luciferase plasmid mcf10a-erbb2 cells 2d-mediated antioxidative effect got1 expressing plasmid primary enzyme facilitating pcmv6-plasmid expressing luc reporter construct independent samples t-test site-directed mutagenesis human pc promoter promotes cancer progression plasmid pgl3-pc intracellular ribose-5-phosphate
Questions {❓}
- The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism: going round in circles?
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