Here's how NATURE.COM makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

NATURE . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Nature.com Make Money
  6. How Much Does Nature.com Make
  7. Keywords
  8. Topics
  9. Questions
  10. Schema
  11. External Links
  12. Analytics And Tracking
  13. Libraries
  14. Hosting Providers
  15. CDN Services

We are analyzing https://www.nature.com/articles/s41380-023-02377-5.

Title:
Techniques for investigating lncRNA transcript functions in neurodevelopment | Molecular Psychiatry
Description:
Long noncoding RNAs (lncRNAs) are sequences of 200 nucleotides or more that are transcribed from a large portion of the mammalian genome. While hypothesized to have a variety of biological roles, many lncRNAs remain largely functionally uncharacterized due to unique challenges associated with their investigation. For example, some lncRNAs overlap with other genomic loci, are expressed in a cell-type-specific manner, and/or are differentially processed at the post-transcriptional level. The mammalian CNS contains a vast diversity of lncRNAs, and lncRNAs are highly abundant in the mammalian brain. However, interrogating lncRNA function in models of the CNS, particularly in vivo, can be complex and challenging. Here we review the breadth of methods used to investigate lncRNAs in the CNS, their merits, and the understanding they can provide with respect to neurodevelopment and pathophysiology. We discuss remaining challenges in the field and provide recommendations to assay lncRNAs based on current methods.
Website Age:
30 years and 10 months (reg. 1994-08-11).

Matching Content Categories {πŸ“š}

  • Education
  • Science
  • Photography

Content Management System {πŸ“}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {πŸ“ˆ}

What is the average monthly size of nature.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {πŸ’Έ}


Display Ads {🎯}


The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.

Ads are managed by yourbow.com. Particular relationships are as follows:

Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.com

Reseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.com

How Much Does Nature.com Make? {πŸ’°}


Display Ads {🎯}

$63,100 per month
According to our algorithms, Nature.com's monthly online income from display advertising ranges from $42,042 to $115,616.

Keywords {πŸ”}

pubmed, article, google, scholar, cas, lncrna, central, lncrnas, rna, expression, gene, crisprcas, noncoding, cell, rnas, targeting, long, brain, vivo, genome, genes, target, nat, dna, activation, nature, functional, mammalian, protein, delivery, editing, loci, cns, sequence, transcription, system, development, approaches, cells, zhang, function, methods, human, transcriptional, approach, endogenous, mol, functions, sgrna, proteins,

Topics {βœ’οΈ}

grant numbers pid2019-111658rb-i00/aei/10 nature portfolio privacy policy rian/mir-144-3p/gata3 signaling advertising crispra-mediated lncrna libraries modulating mir-1224-5p/tgfbr2 axis social media east-seletsky suntag-p65-hsf1 platform high-fidelity crispr/cas13 system generate grna libraries p65-hsf1 fusion protein circular rna research pid2022-142829ob-i00/aei/10 reprints clinically-relevant research predoctoral research award crispr/cas9-mediated genome editing crispr-cas9 genome-editing system crispr/cas9-delineated target site cerebral ischemia-reperfusion injury versatile membrane-bound vesicles crispr/cas9-mediated targeted insertion pten/akt/p21 pathway low gc content neuron-specific promoter-driven expression regulating mir-585-3p/pik3r3 crispr-dcas9-activator transgenic mice crispr/cas-based methods author information authors library construction [39] lncrna-n1lr enhances neuroprotection lncrna mir4435-2hg potentiates unpredictable nature crispr/cas9-mediated gene knock cas9/sgrna ribonucleoprotein complexes potential solutions crispr/cas plasmid delivery preclinical research published article suntag-p65-hsf1 emulate wild-type expression rna-dependent rna targeting crispr-ctrl inserts puromycin crispr-casrx alleviates symptoms universitats/generalitat de catalunya central nervous system limb-specific en1 regulator multi-subunit effector complexes

Questions {❓}

  • NEAT1 and paraspeckles in neurodegenerative diseases: A missing lnc found?

Schema {πŸ—ΊοΈ}

WebPage:
      mainEntity:
         headline:Techniques for investigating lncRNA transcript functions in neurodevelopment
         description:Long noncoding RNAs (lncRNAs) are sequences of 200 nucleotides or more that are transcribed from a large portion of the mammalian genome. While hypothesized to have a variety of biological roles, many lncRNAs remain largely functionally uncharacterized due to unique challenges associated with their investigation. For example, some lncRNAs overlap with other genomic loci, are expressed in a cell-type-specific manner, and/or are differentially processed at the post-transcriptional level. The mammalian CNS contains a vast diversity of lncRNAs, and lncRNAs are highly abundant in the mammalian brain. However, interrogating lncRNA function in models of the CNS, particularly in vivo, can be complex and challenging. Here we review the breadth of methods used to investigate lncRNAs in the CNS, their merits, and the understanding they can provide with respect to neurodevelopment and pathophysiology. We discuss remaining challenges in the field and provide recommendations to assay lncRNAs based on current methods.
         datePublished:2023-12-25T00:00:00Z
         dateModified:2023-12-25T00:00:00Z
         pageStart:874
         pageEnd:890
         license:http://creativecommons.org/licenses/by/4.0/
         sameAs:https://doi.org/10.1038/s41380-023-02377-5
         keywords:
            Biological techniques
            Genetics
            Molecular biology
            Neuroscience
            Medicine/Public Health
            general
            Psychiatry
            Neurosciences
            Behavioral Sciences
            Pharmacotherapy
            Biological Psychology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41380-023-02377-5/MediaObjects/41380_2023_2377_Fig1_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41380-023-02377-5/MediaObjects/41380_2023_2377_Fig2_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41380-023-02377-5/MediaObjects/41380_2023_2377_Fig3_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41380-023-02377-5/MediaObjects/41380_2023_2377_Fig4_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41380-023-02377-5/MediaObjects/41380_2023_2377_Fig5_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41380-023-02377-5/MediaObjects/41380_2023_2377_Fig6_HTML.png
         isPartOf:
            name:Molecular Psychiatry
            issn:
               1476-5578
               1359-4184
            volumeNumber:29
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Tara Srinivas
               affiliation:
                     name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona
                     address:
                        name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Edilene Siqueira
               url:http://orcid.org/0000-0002-8838-2570
               affiliation:
                     name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona
                     address:
                        name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Sonia Guil
               url:http://orcid.org/0000-0002-2257-3331
               affiliation:
                     name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona
                     address:
                        name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
                     name:Germans Trias i Pujol Health Science Research Institute, 08916, Badalona
                     address:
                        name:Germans Trias i Pujol Health Science Research Institute, 08916, Badalona, Barcelona, Spain
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:1
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Techniques for investigating lncRNA transcript functions in neurodevelopment
      description:Long noncoding RNAs (lncRNAs) are sequences of 200 nucleotides or more that are transcribed from a large portion of the mammalian genome. While hypothesized to have a variety of biological roles, many lncRNAs remain largely functionally uncharacterized due to unique challenges associated with their investigation. For example, some lncRNAs overlap with other genomic loci, are expressed in a cell-type-specific manner, and/or are differentially processed at the post-transcriptional level. The mammalian CNS contains a vast diversity of lncRNAs, and lncRNAs are highly abundant in the mammalian brain. However, interrogating lncRNA function in models of the CNS, particularly in vivo, can be complex and challenging. Here we review the breadth of methods used to investigate lncRNAs in the CNS, their merits, and the understanding they can provide with respect to neurodevelopment and pathophysiology. We discuss remaining challenges in the field and provide recommendations to assay lncRNAs based on current methods.
      datePublished:2023-12-25T00:00:00Z
      dateModified:2023-12-25T00:00:00Z
      pageStart:874
      pageEnd:890
      license:http://creativecommons.org/licenses/by/4.0/
      sameAs:https://doi.org/10.1038/s41380-023-02377-5
      keywords:
         Biological techniques
         Genetics
         Molecular biology
         Neuroscience
         Medicine/Public Health
         general
         Psychiatry
         Neurosciences
         Behavioral Sciences
         Pharmacotherapy
         Biological Psychology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41380-023-02377-5/MediaObjects/41380_2023_2377_Fig1_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41380-023-02377-5/MediaObjects/41380_2023_2377_Fig2_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41380-023-02377-5/MediaObjects/41380_2023_2377_Fig3_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41380-023-02377-5/MediaObjects/41380_2023_2377_Fig4_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41380-023-02377-5/MediaObjects/41380_2023_2377_Fig5_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41380-023-02377-5/MediaObjects/41380_2023_2377_Fig6_HTML.png
      isPartOf:
         name:Molecular Psychiatry
         issn:
            1476-5578
            1359-4184
         volumeNumber:29
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Tara Srinivas
            affiliation:
                  name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona
                  address:
                     name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Edilene Siqueira
            url:http://orcid.org/0000-0002-8838-2570
            affiliation:
                  name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona
                  address:
                     name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Sonia Guil
            url:http://orcid.org/0000-0002-2257-3331
            affiliation:
                  name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona
                  address:
                     name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
                  name:Germans Trias i Pujol Health Science Research Institute, 08916, Badalona
                  address:
                     name:Germans Trias i Pujol Health Science Research Institute, 08916, Badalona, Barcelona, Spain
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:1
["Periodical","PublicationVolume"]:
      name:Molecular Psychiatry
      issn:
         1476-5578
         1359-4184
      volumeNumber:29
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona
      address:
         name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
         type:PostalAddress
      name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona
      address:
         name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
         type:PostalAddress
      name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona
      address:
         name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
         type:PostalAddress
      name:Germans Trias i Pujol Health Science Research Institute, 08916, Badalona
      address:
         name:Germans Trias i Pujol Health Science Research Institute, 08916, Badalona, Barcelona, Spain
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Tara Srinivas
      affiliation:
            name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona
            address:
               name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Edilene Siqueira
      url:http://orcid.org/0000-0002-8838-2570
      affiliation:
            name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona
            address:
               name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      name:Sonia Guil
      url:http://orcid.org/0000-0002-2257-3331
      affiliation:
            name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona
            address:
               name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
               type:PostalAddress
            type:Organization
            name:Germans Trias i Pujol Health Science Research Institute, 08916, Badalona
            address:
               name:Germans Trias i Pujol Health Science Research Institute, 08916, Badalona, Barcelona, Spain
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
      name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
      name:Josep Carreras Leukaemia Research Institute (IJC), 08916, Badalona, Barcelona, Spain
      name:Germans Trias i Pujol Health Science Research Institute, 08916, Badalona, Barcelona, Spain

External Links {πŸ”—}(649)

Analytics and Tracking {πŸ“Š}

  • Google Tag Manager

Libraries {πŸ“š}

  • Particles.js
  • Prism.js
  • Zoom.js

Emails and Hosting {βœ‰οΈ}

Mail Servers:

  • mxa-002c5801.gslb.pphosted.com
  • mxb-002c5801.gslb.pphosted.com

Name Servers:

  • pdns1.ultradns.net
  • pdns2.ultradns.net
  • pdns3.ultradns.org
  • pdns4.ultradns.org
  • pdns5.ultradns.info
  • pdns6.ultradns.co.uk

CDN Services {πŸ“¦}

  • Crossref

6.49s.