Here's how NATURE.COM makes money* and how much!

*Please read our disclaimer before using our estimates.
Loading...

NATURE . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Nature.com Make Money
  6. How Much Does Nature.com Make
  7. Keywords
  8. Topics
  9. Questions
  10. Schema
  11. Social Networks
  12. External Links
  13. Analytics And Tracking
  14. Libraries
  15. Hosting Providers
  16. CDN Services

We are analyzing https://www.nature.com/articles/s41580-020-0232-1.

Title:
The clearance of dead cells by efferocytosis | Nature Reviews Molecular Cell Biology
Description:
Multiple modes of cell death have been identified, each with a unique function and each induced in a setting-dependent manner. As billions of cells die during mammalian embryogenesis and daily in adult organisms, clearing dead cells and associated cellular debris is important in physiology. In this Review, we present an overview of the phagocytosis of dead and dying cells, a process known as efferocytosis. Efferocytosis is performed by macrophages and to a lesser extent by other ‘professional’ phagocytes (such as monocytes and dendritic cells) and ‘non-professional’ phagocytes, such as epithelial cells. Recent discoveries have shed light on this process and how it functions to maintain tissue homeostasis, tissue repair and organismal health. Here, we outline the mechanisms of efferocytosis, from the recognition of dying cells through to phagocytic engulfment and homeostatic resolution, and highlight the pathophysiological consequences that can arise when this process is abrogated. Development and homeostasis are dependent on rapid cell turnover, achieved by the programmed death and subsequent engulfment and breakdown of cells, a process known as efferocytosis. Defects in efferocytosis have been linked to a wide range of diseases; ongoing research therefore aims to better understand efferocytosis processes so as to uncover new therapeutic targets.
Website Age:
30 years and 10 months (reg. 1994-08-11).

Matching Content Categories {📚}

  • Education
  • Science
  • Telecommunications

Content Management System {📝}

What CMS is nature.com built with?

Custom-built

No common CMS systems were detected on Nature.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of nature.com audience?

🌆 Monumental Traffic: 20M - 50M visitors per month


Based on our best estimate, this website will receive around 42,799,894 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Nature.com Make Money? {💸}


Display Ads {🎯}


The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.

Ads are managed by yourbow.com. Particular relationships are as follows:

Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.com

Reseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.com

How Much Does Nature.com Make? {💰}


Display Ads {🎯}

$539,300 per month
Estimations show Nature.com's display ad online revenue falls between $359,561 and $988,793 per month.

Keywords {🔍}

pubmed, article, google, scholar, cas, central, cell, cells, apoptotic, nature, biol, immunol, clearance, death, phagocytosis, inflammation, protein, macrophages, apoptosis, rev, efferocytosis, activation, nat, disease, macrophage, receptor, sci, signaling, immune, mol, membrane, tissue, response, inflammatory, molecular, role, recognition, signal, release, immunity, liver, dying, med, atherosclerosis, heckmann, green, engulfment, access, usa, cancer,

Topics {✒️}

permissions reprints research triangle park privacy policy nature portfolio journals author information authors scientific advisory board research hospital nature portfolio advertising social media intestinal epithelium-basic biology transforming growth factor-beta γ-aminobutyric acid receptor calcium-dependent phospholipid scrambling anti-hypertensive drug spironolactone cyclic gmp-amp synthase gamma-carboxyglutamic acid modification peroxisome proliferator-activated receptor mfg-e8 null mutations murine ischemia/reperfusion injury suppress pro-inflammatory eicosanoid coordinately induce anti-inflammatory bleomycin-induced lung injury gas6-axl-nlrp3 axis anti-nuclear antibodies complexed irg1/itaconate enhances efferocytosis �professional’ phagocytes professional’ phagocytes antiapoptotic mediator sphingosine-1-phosphate late-onset autoimmune syndrome anti-inflammatory mechanisms triggered end-directed vesicle transport mfg-e8-dependent clearance personal data embo long-term fellowship promotes anti-tumor immunity xk-related protein 8 elmo/dock180/rac module article boada-romero peer review efferocytosis emilio boada-romero apoptotic human t-cells phosphatidylserine-dependent homeostatic response permissions cell death based dominant pro-phagocytic signal data protection multiple human cancers springerlink instant access fatty acid oxidation

Questions {❓}

  • Macrophage reverse cholesterol transport: key to the regression of atherosclerosis?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:The clearance of dead cells by efferocytosis
         description:Multiple modes of cell death have been identified, each with a unique function and each induced in a setting-dependent manner. As billions of cells die during mammalian embryogenesis and daily in adult organisms, clearing dead cells and associated cellular debris is important in physiology. In this Review, we present an overview of the phagocytosis of dead and dying cells, a process known as efferocytosis. Efferocytosis is performed by macrophages and to a lesser extent by other ‘professional’ phagocytes (such as monocytes and dendritic cells) and ‘non-professional’ phagocytes, such as epithelial cells. Recent discoveries have shed light on this process and how it functions to maintain tissue homeostasis, tissue repair and organismal health. Here, we outline the mechanisms of efferocytosis, from the recognition of dying cells through to phagocytic engulfment and homeostatic resolution, and highlight the pathophysiological consequences that can arise when this process is abrogated. Development and homeostasis are dependent on rapid cell turnover, achieved by the programmed death and subsequent engulfment and breakdown of cells, a process known as efferocytosis. Defects in efferocytosis have been linked to a wide range of diseases; ongoing research therefore aims to better understand efferocytosis processes so as to uncover new therapeutic targets.
         datePublished:2020-04-06T00:00:00Z
         dateModified:2020-04-06T00:00:00Z
         pageStart:398
         pageEnd:414
         sameAs:https://doi.org/10.1038/s41580-020-0232-1
         keywords:
            Cell death
            Cell death and immune response
            Life Sciences
            general
            Cell Biology
            Cancer Research
            Developmental Biology
            Stem Cells
            Biochemistry
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-020-0232-1/MediaObjects/41580_2020_232_Fig1_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-020-0232-1/MediaObjects/41580_2020_232_Figa_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-020-0232-1/MediaObjects/41580_2020_232_Fig2_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-020-0232-1/MediaObjects/41580_2020_232_Fig3_HTML.png
         isPartOf:
            name:Nature Reviews Molecular Cell Biology
            issn:
               1471-0080
               1471-0072
            volumeNumber:21
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Nature Publishing Group UK
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Emilio Boada-Romero
               affiliation:
                     name:St. Jude Children’s Research Hospital
                     address:
                        name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Jennifer Martinez
               affiliation:
                     name:Inflammation & Autoimmunity Group, National Institute for Environmental Health Sciences, Research Triangle Park
                     address:
                        name:Inflammation & Autoimmunity Group, National Institute for Environmental Health Sciences, Research Triangle Park, Durham, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Bradlee L. Heckmann
               url:http://orcid.org/0000-0002-3271-7183
               affiliation:
                     name:St. Jude Children’s Research Hospital
                     address:
                        name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Douglas R. Green
               url:http://orcid.org/0000-0002-7332-1417
               affiliation:
                     name:St. Jude Children’s Research Hospital
                     address:
                        name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:The clearance of dead cells by efferocytosis
      description:Multiple modes of cell death have been identified, each with a unique function and each induced in a setting-dependent manner. As billions of cells die during mammalian embryogenesis and daily in adult organisms, clearing dead cells and associated cellular debris is important in physiology. In this Review, we present an overview of the phagocytosis of dead and dying cells, a process known as efferocytosis. Efferocytosis is performed by macrophages and to a lesser extent by other ‘professional’ phagocytes (such as monocytes and dendritic cells) and ‘non-professional’ phagocytes, such as epithelial cells. Recent discoveries have shed light on this process and how it functions to maintain tissue homeostasis, tissue repair and organismal health. Here, we outline the mechanisms of efferocytosis, from the recognition of dying cells through to phagocytic engulfment and homeostatic resolution, and highlight the pathophysiological consequences that can arise when this process is abrogated. Development and homeostasis are dependent on rapid cell turnover, achieved by the programmed death and subsequent engulfment and breakdown of cells, a process known as efferocytosis. Defects in efferocytosis have been linked to a wide range of diseases; ongoing research therefore aims to better understand efferocytosis processes so as to uncover new therapeutic targets.
      datePublished:2020-04-06T00:00:00Z
      dateModified:2020-04-06T00:00:00Z
      pageStart:398
      pageEnd:414
      sameAs:https://doi.org/10.1038/s41580-020-0232-1
      keywords:
         Cell death
         Cell death and immune response
         Life Sciences
         general
         Cell Biology
         Cancer Research
         Developmental Biology
         Stem Cells
         Biochemistry
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-020-0232-1/MediaObjects/41580_2020_232_Fig1_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-020-0232-1/MediaObjects/41580_2020_232_Figa_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-020-0232-1/MediaObjects/41580_2020_232_Fig2_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fs41580-020-0232-1/MediaObjects/41580_2020_232_Fig3_HTML.png
      isPartOf:
         name:Nature Reviews Molecular Cell Biology
         issn:
            1471-0080
            1471-0072
         volumeNumber:21
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Nature Publishing Group UK
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Emilio Boada-Romero
            affiliation:
                  name:St. Jude Children’s Research Hospital
                  address:
                     name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jennifer Martinez
            affiliation:
                  name:Inflammation & Autoimmunity Group, National Institute for Environmental Health Sciences, Research Triangle Park
                  address:
                     name:Inflammation & Autoimmunity Group, National Institute for Environmental Health Sciences, Research Triangle Park, Durham, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Bradlee L. Heckmann
            url:http://orcid.org/0000-0002-3271-7183
            affiliation:
                  name:St. Jude Children’s Research Hospital
                  address:
                     name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Douglas R. Green
            url:http://orcid.org/0000-0002-7332-1417
            affiliation:
                  name:St. Jude Children’s Research Hospital
                  address:
                     name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Nature Reviews Molecular Cell Biology
      issn:
         1471-0080
         1471-0072
      volumeNumber:21
Organization:
      name:Nature Publishing Group UK
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:St. Jude Children’s Research Hospital
      address:
         name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
         type:PostalAddress
      name:Inflammation & Autoimmunity Group, National Institute for Environmental Health Sciences, Research Triangle Park
      address:
         name:Inflammation & Autoimmunity Group, National Institute for Environmental Health Sciences, Research Triangle Park, Durham, USA
         type:PostalAddress
      name:St. Jude Children’s Research Hospital
      address:
         name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
         type:PostalAddress
      name:St. Jude Children’s Research Hospital
      address:
         name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Emilio Boada-Romero
      affiliation:
            name:St. Jude Children’s Research Hospital
            address:
               name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
               type:PostalAddress
            type:Organization
      name:Jennifer Martinez
      affiliation:
            name:Inflammation & Autoimmunity Group, National Institute for Environmental Health Sciences, Research Triangle Park
            address:
               name:Inflammation & Autoimmunity Group, National Institute for Environmental Health Sciences, Research Triangle Park, Durham, USA
               type:PostalAddress
            type:Organization
      name:Bradlee L. Heckmann
      url:http://orcid.org/0000-0002-3271-7183
      affiliation:
            name:St. Jude Children’s Research Hospital
            address:
               name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Douglas R. Green
      url:http://orcid.org/0000-0002-7332-1417
      affiliation:
            name:St. Jude Children’s Research Hospital
            address:
               name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
      name:Inflammation & Autoimmunity Group, National Institute for Environmental Health Sciences, Research Triangle Park, Durham, USA
      name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
      name:Department of Immunology, St. Jude Children’s Research Hospital, Memphis, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

Social Networks {👍}(2)

External Links {🔗}(906)

Analytics and Tracking {📊}

  • Google Tag Manager

Libraries {📚}

  • Prism.js
  • Zoom.js

Emails and Hosting {✉️}

Mail Servers:

  • mxa-002c5801.gslb.pphosted.com
  • mxb-002c5801.gslb.pphosted.com

Name Servers:

  • pdns1.ultradns.net
  • pdns2.ultradns.net
  • pdns3.ultradns.org
  • pdns4.ultradns.org
  • pdns5.ultradns.info
  • pdns6.ultradns.co.uk

CDN Services {📦}

  • Crossref

6.72s.