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Keywords {🔍}

skin, mice, fig, pubmed, lipid, article, diet, scholar, google, lipids, data, skins, cas, fat, dietary, supplementary, epidermis, adipose, sebome, acyl, fed, central, days, dwat, properties, heat, tissue, weeks, increased, female, hair, consumption, feeding, metabolic, energy, thermal, high, body, shown, nature, total, function, epidermal, cell, hfd, cbl, ceramides, specific, species, wdil,

Topics {✒️}

nature portfolio privacy policy lc/q-tof mass spectrometry hrp-conjugated anti-rabbit antibody /scientific-software/prism editing sera-specific libraries proteo-lipid cross-linked sheath advertising closely-apposed lipid-enriched layers nature 451 nature social media epidermal acyl-coa-binding protein diabetes research center lower mitotic index peer review file cross-linked proteolipid matrix reprints lc/qtof-ms spectra branched-chain amino acids fourier-transform mass spectrometry cross-linked stratum corneum27 lc/qtof-ms confirmed short-chain fatty acids acyl-coa-binding protein author information authors mitotic index long-chain fatty acids low-isoleucine western diet chain-melting transition temperatures methyl tert-butyl ether keratinocyte/sebocyte-enriched tissue fraction free access peer review poly-unsaturated acyl chains high fat-diet feeding β-adrenergic-resistant depot amino acid-defined wd health-promoting diet interventions source data files multi-modal lipid profiling imiquimod-induced psoriasiform dermatitis multi-modal lipidomic analysis wdil-fed mice resisted wdil-fed mice revealed ether-linked oxidized phosphatidylcholines cold elastase/dmem/hepes permissions multi-modal lipid analysis

Questions {❓}

• Cutaneous changes in diabetic patients: Primed for aberrant healing?
• Does skin offer a means of excess lipid disposal?
• How important is thermal adaptation of skin to insulation, energetics and metabolic health of mammals?
• Which cellular components are implicated in functional responses?
• Which lipid components correlate with altered thermal barrier function?

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      headline:Dietary lipids are largely deposited in skin and rapidly affect insulating properties
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