We are analyzing https://link.springer.com/chapter/10.1007/978-3-030-21735-8_15.

Title:
Roles of Ceramides and Other Sphingolipids in Immune Cell Function and Inflammation | SpringerLink
Description:
Ceramides are bioactive sphingolipids that support the structure of the plasma membrane and mediate numerous cell-signaling events in eukaryotic cells. The finding that ceramides act as second messengers transducing cellular signals has attracted substantial...
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Topics {✒️}

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Schema {🗺️}

ScholarlyArticle:
      headline:Roles of Ceramides and Other Sphingolipids in Immune Cell Function and Inflammation
      pageEnd:191
      pageStart:169
      image:https://media.springernature.com/w153/springer-static/cover/book/978-3-030-21735-8.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:The Role of Bioactive Lipids in Cancer, Inflammation and Related Diseases
         isbn:
            978-3-030-21735-8
            978-3-030-21636-8
         type:Book
      publisher:
         name:Springer International Publishing
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Sabrin Albeituni
            affiliation:
                  name:St. Jude Children’s Research Hospital
                  address:
                     name:Department of Oncology, St. Jude Children’s Research Hospital, Memphis, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Johnny Stiban
            affiliation:
                  name:Birzeit University
                  address:
                     name:Department of Biology and Biochemistry, Birzeit University, West Bank, Palestine
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      keywords:Ceramides, Immune cells, Sphingolipids, Inflammation, Disease
      description:Ceramides are bioactive sphingolipids that support the structure of the plasma membrane and mediate numerous cell-signaling events in eukaryotic cells. The finding that ceramides act as second messengers transducing cellular signals has attracted substantial attention in several fields of Biology. Since all cells contain lipid plasma membranes, the impact of various ceramides, ceramide synthases, ceramide metabolites, and other sphingolipids has been implicated in a vast range of cellular functions including, migration, proliferation, response to external stimuli, and death. The roles of lipids in these functions widely differ among the diverse cell types. Herein, we discuss the roles of ceramides and other sphingolipids in mediating the function of various immune cells; particularly dendritic cells, neutrophils, and macrophagesMacrophages. In addition, we highlight the main studies describing effects of ceramides in inflammation, specifically in various inflammatory settings including insulin resistance, graft-versus-host disease, immune suppression in cancer, multiple sclerosis, and inflammatory bowel disease.
      datePublished:2019
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Book:
      name:The Role of Bioactive Lipids in Cancer, Inflammation and Related Diseases
      isbn:
         978-3-030-21735-8
         978-3-030-21636-8
Organization:
      name:Springer International Publishing
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:St. Jude Children’s Research Hospital
      address:
         name:Department of Oncology, St. Jude Children’s Research Hospital, Memphis, USA
         type:PostalAddress
      name:Birzeit University
      address:
         name:Department of Biology and Biochemistry, Birzeit University, West Bank, Palestine
         type:PostalAddress
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      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Sabrin Albeituni
      affiliation:
            name:St. Jude Children’s Research Hospital
            address:
               name:Department of Oncology, St. Jude Children’s Research Hospital, Memphis, USA
               type:PostalAddress
            type:Organization
      name:Johnny Stiban
      affiliation:
            name:Birzeit University
            address:
               name:Department of Biology and Biochemistry, Birzeit University, West Bank, Palestine
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Oncology, St. Jude Children’s Research Hospital, Memphis, USA
      name:Department of Biology and Biochemistry, Birzeit University, West Bank, Palestine
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