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Title[redir]:
Interferon-induced guanylate-binding proteins in inflammasome activation and host defense | Nature Immunology
Description:
In this Perspective, MacMicking and colleagues discuss the roles of interferon-induced guanylate-binding proteins in directing inflammasome responses and their effects on immunity to a wide variety of microbial pathogens. Traditional views of the inflammasome highlight the assembly of pre-existing core components shortly after infection or tissue damage. Emerging work, however, suggests that the inflammasome machinery is also subject to
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pubmed, article, google, scholar, cas, central, inflammasome, nature, immunol, activation, cell, guanylatebinding, proteins, nat, host, protein, caspase, macmicking, immunity, human, access, science, defense, toxoplasma, infection, usa, gondii, gtpases, inflammasomes, rev, guanylate, binding, content, kim, sci, nlrp, noncanonical, role, biol, cookies, interferon, gbp, proc, natl, acad, aim, intracellular, plos, privacy, data,
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nature portfolio permissions reprints privacy policy ifn-γ-activated human cells ifn-γ-induced cell-autonomous responses interferon-induced guanylate-binding proteins advertising ifn-γ-induced macrophage immunity social media zebrafish guanylate-binding protein murine guanylate-binding protein sqstm1/p62/a170 regulates author information authors tnf-α mediates sensitization development ifn-induced gtpases mgbp1 ifn-γ-inducible lrg-47 interferon-γ-induced presentation caspase-1-deficient mice infected inflammasome-activating molecular component human autophagy proteins c-terminal α-helices host-virus arms races hsv-1-induced inflammasome activation author correspondence inflammatory diseases lps-induced inos production guanylate-binding proteins guanylate binding proteins ifn-γ primes keratinocytes personal data interferon-inducible effector mechanisms mouse p47-resistance gtpases tlr4-independent endotoxic shock nature 509 nature 526 nature 479 nature 514 nature 490 nature 458 nature 488 nature 440 nature pathogen-induced cell death guanylate-binding protein 1 data protection springerlink instant access cell-autonomous immunity protects ifn-inducible gtpases ifn-induced gtpases
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Mail Servers:
- mx.zoho.eu
- mx2.zoho.eu
- mx3.zoho.eu
Name Servers:
- josh.ns.cloudflare.com
- zita.ns.cloudflare.com
CDN Services {📦}
- Crossref