
NCBI . NLM . NIH . GOV {
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Title[redir]:
Emerging themes in IFN-γ-induced macrophage immunity by the p47 and p65 GTPase Families - PMC
Description:
Vertebrates have evolved complex immune specificity repertoires beyond the primordial components found in lower multi-cellular organisms to combat microbial infections. The type II interferon (IFN-γ) pathway represents one such system, bridging ...
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Keywords {🔍}
doi, pubmed, google, scholar, gbps, irgs, pmc, irg, macmicking, binding, article, gtpase, free, protein, human, proteins, iigpirga, gtpases, martens, gbp, activity, taylor, fig, family, genes, mouse, lrgirgm, hgbp, gene, macrophages, cell, howard, members, gtp, site, biol, guanylatebinding, unpublished, science, interferon, host, membrane, gondii, resistance, intracellular, immunol, complex, activation, vestal, igtpirgm,
Topics {✒️}
interferon-gamma-induced gtp-binding protein transition-state analog-bound hgbp1 interferon-gamma-inducible 47-kda gtpase enhance ifn-γ-induced activation [pubmed] [google scholar] ifn-gamma-inducible gene igtp ifn-γ-dependent gene expression full-length dimeric iigp1/irgb6 interferon-gamma-induced chromatin remodeling ifn-γ-induced macrophage immunity nf-κb binding site ifn-γ-activated mouse macrophages c-terminal helical domains ifn-gamma-inducible cofactor lower multi-cellular organisms phosphoaminophosphonic acid-guanylate ester murine guanylate-binding protein pmc beta search guanylate-binding protein-1 expression medicine cox-browne fellowship interferon-gamma-induced cytokine monomeric full-length hgbp1 brefeldin a-sensitive pathway related interferon-induced gtpases c-terminal gtpase domains key swi/snf complex ifn-gamma-inducible lrg-47 nuclear factor-kappab motif ikappab kinase-related kinases disparate nucleotide-binding specificities human recombinant interferon-gamma phosphatidylinositol 3-kinase/akt pathway ifn-γ-stimulated proteins interferon gamma-inducible genes ifn-γ-activated raw264 interferon-gamma activated site goat anti-lrg-47 peptide cytokine-induced promoter assembly subsequent irf-1-driven transcription n-terminal myristoylation site n-terminal gtpase domain adaptor inducing ifn-β ifn-γ priming heightens heterotrimeric stat-1/stat-2/irf-9 gamma interferon-induced inhibition long-recognized antimicrobial activity pre-fusion pore complexes ikk-related kinase ikkε irg-47 g-protein gene p65 guanylate-binding proteins
Questions {❓}
- Different subcellular localizations for the related interferon-induced GTPases, MuGBP-1 and MuGBP-2: implications for different functions?
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- Financial intake of https://scholar.google.com/scholar_lookup?journal=J%20Exp%20Med&title=Identification%20of%20interferon-gamma%20as%20the%20lymphokine%20that%20activates%20human%20macrophage%20oxidative%20metabolism%20and%20antimicrobial%20activity&author=CF%20Nathan&author=HW%20Murray&author=ME%20Wiebe&author=BY%20Rubin&volume=158&publication_year=1983&pages=670-689&pmid=6411853&doi=10.1084/jem.158.3.670&
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- https://doi.org/10.1073/pnas.97.16.8841's revenue stream
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- https://doi.org/10.1016/j.jmb.2004.09.026's total income per month
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- Find out how much https://doi.org/10.1146/annurev.med.49.1.275 earns monthly
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- Monthly income for https://doi.org/10.1038/nri1270
- https://scholar.google.com/scholar_lookup?journal=Nat%20Rev%20Immunol&title=p47%20GTPases:%20regulators%20of%20immunity%20to%20intracellular%20pathogens&author=GA%20Taylor&author=CG%20Feng&author=A%20Sher&volume=4&publication_year=2004&pages=100-109&pmid=15040583&doi=10.1038/nri1270&'s financial summary
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- Get to know https://scholar.google.com/scholar_lookup?journal=J%20Interferon%20Cytokine%20Res&title=Different%20subcellular%20localizations%20for%20the%20related%20interferon-induced%20GTPases,%20MuGBP-1%20and%20MuGBP-2:%20implications%20for%20different%20functions?&author=DJ%20Vestal&author=VY%20Gorbacheva&author=GC%20Sen&volume=20&publication_year=2000&pages=991-1000&pmid=11096456&doi=10.1089/10799900050198435&'s earnings
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- How much revenue does https://doi.org/10.1038/nature01262 generate?
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- https://doi.org/10.4049/jimmunol.168.7.3428's financial summary
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- See how much https://scholar.google.com/scholar_lookup?journal=J%20Biol%20Chem&title=Overexpression%20of%20interferon-gamma-inducible%20GTPase%20inhibits%20coxsackievirus%20B3-induced%20apoptosis%20through%20the%20activation%20of%20the%20phosphatidylinositol%203-kinase/Akt%20pathway%20and%20inhibition%20of%20viral%20replication&author=HM%20Zhang&author=J%20Yuan&author=P%20Cheung&author=H%20Luo&author=B%20Yanagawa&volume=278&publication_year=2003&pages=33011-33019&pmid=12819192&doi=10.1074/jbc.M305352200& makes per month
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