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Oxidative stress and the ageing endocrine system | Nature Reviews Endocrinology
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A progressive decline in cellular function and organismal fitness and an increase in age-related diseases are associated with ageing; many theories have attempted to explain this phenomenon. This Review outlines the current knowledge of the effects of oxidative stress on endocrine organs and tissues and suggests that inflammation is the link between oxidative stress and ageing. Ageing is a process characterized by a progressive decline in cellular function, organismal fitness and increased risk of age-related diseases and death. Several hundred theories have attempted to explain this phenomenon. One of the most popular is the
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