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nature portfolio permissions reprints privacy policy immunofluorescence-combined single-molecule rna-fish open-source platform accession number gse78030 advertising egfp-expressing shdc1-transfected cells promotes cap-independent translation social media female mammalian development author information authors u-rich rna-binding motifs sirbm15/sirbm15b double-knockdown sample primary micro rna wtap-dependent mettl3–rbm15/15b interaction epitranscriptome nature uracil-rich hnrnpc-binding motif transcriptome-wide rna-binding sites ejc-sr protein nexus n6-methyladenosine-dependent regulation reversible cross-linking combined representative rna-fish images activate gene-silencing mechanisms xist-mediated transcriptional repression mettl3/rbm15/15b-dependent manner single-nucleotide-resolution mapping nature 379 nature 521 nature 485 nature 505 nature 518 nature 537 nature xist-mediated transcriptional silencing xist-mediated gene silencing rbm15/15b–wtap–mettl3 complex x-linked gene silencing crispr-mediated homozygous knockout exploring deep-sequencing data weill-cornell medical college author correspondence rbm15/15b-binding sites show xist rna-mediated silencing rna n6-methyladenosine methyltransferase bio-imaging resource center pew-stewart scholars program rna n6-methyladenosine modification normal xist-induced silencing tailed mann–whitney test

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